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| 妊娠滋养细胞肿瘤免疫组织化学研究 | |
| 引用本文： | 王美清,袁而恩,李素英,于惠霞,逄黎毅. 妊娠滋养细胞肿瘤免疫组织化学研究[J]. 山东大学学报(医学版), 1989, 0(3) |
| 作者姓名： | 王美清 袁而恩 李素英 于惠霞 逄黎毅 |
| 作者单位： | 山东医科大学病理解剖学教研窒(王美清，袁而恩，李素英)，山东医科大学附属医院妇产科(于惠霞)，山东医科大学附属医院妇产科(逄黎毅) |
| 摘 要： | 观察hCG,hPL在15例葡萄胎、17例恶性葡萄胎及15例绒毛膜癌中的分布,证实有中间型滋养细胞。hCG和hPL在IT和ST中的含量随滋养细胞肿瘤的不同而异,ST可能含hCG或hPL,IT主要含hPL,CT不含hCG,也无hPL。 |
| 关 键 词： | 促性腺激素类 绒毛膜 胎盘催乳激素 滋养层肿瘤 妊娠 中间性滋养细胞 |
AN IMMUNOHISTOCHEMICAL STUDY ON THE DISTRIBUTION OF HUMAN CHORIONIC GONADOTROPIN(hCG)AND HUMAN PLACENTAL LACTOGEN(hPL)IN GESTATIONAL TROPHOBLASTIC TUMORS |
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| Wang Meiqing,et al Dept.of Pathology,Shandong Medical University. AN IMMUNOHISTOCHEMICAL STUDY ON THE DISTRIBUTION OF HUMAN CHORIONIC GONADOTROPIN(hCG)AND HUMAN PLACENTAL LACTOGEN(hPL)IN GESTATIONAL TROPHOBLASTIC TUMORS[J]. Journal of Shandong University:Health Sciences, 1989, 0(3) | |
| Authors: | Wang Meiqing et al Dept.of Pathology Shandong Medical University |
| Abstract: | This report presents a preliminary observation of the im-munohistochemical localization of hCG and hPL in 15 cases of hydatidi-form moles,17 cases of invasive moles and 15 cases of choriocarcinoma.An intermediate type of trophoblast(IT)was identified in the gestationaltrophoblastic tumors.The localization of hCG and hPL in both IT andsyncytiotrophoblast(ST)varied with types of trophoblastic tumors.Syncytiotrophoblast sometimes contained both hormones,whereas IT con-tained hPL predominantly.Cytotrophoblast were devoid of hCG and hPLexcept in choriocarcinoma.The origin of IT and the hormone-producingtrophoblast is discussed briefly.Because a large number of IT wereobserved in the invasive mole,the authors propose that a serologic deter-mination of both hCG and hPL levels may be helpful in differentiatinginvasive moles from choriocarcinoma. |
| Keywords: | Gonadotropins chorionic human Placental lactogen Trophoblastic tumor Pregnancy Intermediate trophoblast |
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