| 螺旋藻多糖对人宫颈癌Hela细胞体外生长的影响 |
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| 引用本文： | 丁守怡,杨英.螺旋藻多糖对人宫颈癌Hela细胞体外生长的影响[J].青岛大学医学院学报,2002,38(4):340-347. |
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| 作者姓名： | 丁守怡 杨英 |
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| 作者单位： | 1. 青岛大学医学院微生物学教研室,青岛,266021
2. 青岛大学医学院附属医院药剂科,青岛,266021 |
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| 摘 要： | 目的：探讨螺旋藻多糖（PSP）对体外培养的Hela细胞生长的影响。方法：采用MTT法测定 PSP的抗肿瘤活性，并观察其对Hela细胞形态学的影响。结果：随PSP浓度的升高，Hela细胞存活率逐渐降低，抑制率逐渐增加；光镜下观察显示，PSP作用24-48h后，细胞出现明显的形态学改变。结论：PSP能抑制Hela细胞增殖。
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| 关 键 词： | 螺旋藻多糖 宫颈肿瘤 Hela细胞 细胞分裂 MTT比色法 |
| 文章编号： | 1001-4047(2002)04-0346-02 |
| 修稿时间： | 2002年6月4日 |
EFFECTS OF POLYSACCHARIDES FROM SPIRULINA PLATENSIS ON THE GROWTH OF Hela CELLS: AN IN VITRO STUDY |
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| DING Shouyi,YANG Ying \.EFFECTS OF POLYSACCHARIDES FROM SPIRULINA PLATENSIS ON THE GROWTH OF Hela CELLS: AN IN VITRO STUDY[J].Acta Academiae Medicinae Qingdao Universitatis,2002,38(4):340-347. |
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| Authors: | DING Shouyi YANG Ying \ |
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| Institution: | DING Shouyi,YANG Ying \ Department of Microbiology,Qingdao University Medical College,Qingdao 266021 |
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| Abstract: | Objective\ To study the effects of polysaccharide from Spirulina platensis (PSP) on the growth of Hela cells in vitro. \ Methods\ MTT assay was applied to evaluate the antitumor activity of PSP on Hela cells and its influence on the cell morphological changes was observed. \ Results\ With the increase of PSP concentration , the inhibition rate on Hela cells increased and the survival rate declined. Evident morphological changes of Hela cells, exposed to PSP for 24-48 hours, were seen microscopically. \ Conclusion\ PSP can inhibit the proliferation of Hela cells. |
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| Keywords: | polysaccharides from Spirulina platensis cervix neoplasms Hela cells cell division MTT chromatometry |
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