Identification of a novel DRB1*04 allele: DRB1*0445 |
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| Authors: | Bae S-C Lee K W |
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| Affiliation: | Department of Internal Medicine, Division of Rheumatology, Hanyang University College of Medicine, Seoul, Korea. |
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| Abstract: | ![]()
The novel allele DRB1*0445 differs from DRB1*04051 by a single nucleotide substitution at codon 23 (CGG-->CCG), resulting in an amino-acid change from arginine to proline. The haplotype associated with the novel allele is A*2402-B*5401-Cw*0102-DRB1*0445-DRB4*01-DQB1*0302. |
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| Keywords: | DRB1*0445 HLA-DR4 novel allele PCR-SBT |
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