| 芒果苷的药效作用研究进展 |
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| 引用本文： | 范香成,焦广洋,张凤,韩军,陈万生.芒果苷的药效作用研究进展[J].第二军医大学学报,2024,45(2). |
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| 作者姓名： | 范香成 焦广洋 张凤 韩军 陈万生 |
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| 作者单位： | 海军军医大学第二附属医院（上海长征医院）,上海中医药大学,海军军医大学第二附属医院（上海长征医院）,海军军医大学第二附属医院,海军军医大学第二附属医院 |
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| 基金项目： | 国家自然科学基金资助项目(81830109),金子塔人才工程(0806和1016),创新型临床研究资助项目(2020YLCYJ-Y25). Supported by National Natural Science Foundation of China (81830109), Jin-Zi-Ta Talent projects (0806 and 1016), and Innovative Clinical Research Funding Project (2020YLCYJ-Y25). |
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| 摘 要： | 芒果苷是一种天然存在的C-葡萄糖基黄酮，是有效的药用化合物，可以从多种植物中分离提取得到。研究表明，芒果苷具有治疗糖尿病、抗肿瘤、抗炎、抗氧化、治疗眼部疾病、神经系统保护、肾脏保护、改善心血管疾病等作用。由于其具有众多的生物活性，对预防和治疗多种疾病有巨大潜力。本文对近年来芒果苷的药效学研究进展及其作用机制进行综述，以期为芒果苷的进一步研究和利用提供科学依据。
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| 关 键 词： | 芒果苷 黄酮 防治糖尿病 作用机制 |
| 收稿时间： | 2022/5/11 0:00:00 |
| 修稿时间： | 2022/10/8 0:00:00 |
Research progress in pharmacodynamics of mangiferin |
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| FAN Xiang-cheng,JIAO Guang-yang,ZHANG Feng,HAN Jun and CHEN Wan-sheng.Research progress in pharmacodynamics of mangiferin[J].Academic Journal of Second Military Medical University,2024,45(2). |
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| Authors: | FAN Xiang-cheng JIAO Guang-yang ZHANG Feng HAN Jun and CHEN Wan-sheng |
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| Institution: | Department of Pharmacy,Changzheng Hospital,Naval Medical University Second Military Medical University, Shanghai, China,Institute of Chinese Materia Madica,Shanghai University of Traditional Chinese Medicine, Shanghai, China,Department of Pharmacy,Changzheng Hospital,Naval Medical University Second Military Medical University, Shanghai, China,Department of Gastroenterology,Changzheng Hospital,Naval Medical University Second Military Medical University,Department of Pharmacy,Changzheng Hospital,Naval Medical University Second Military Medical University Shanghai |
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| Abstract: | Mangiferin is a naturally derived C-glucosyl flavonoid, which can be isolated from many plants as a potent pharmaceutical compound. Previous studies indicated that mangiferin exert an array of pharmacological activities, including anti-diabetes, anti-tumor, anti-inflammation, anti-oxidation, treatment of eye diseases, nervous system protection, kidney protection, and improvement of cardiovascular diseases. Due to its numerous biological activities, mangiferin has great potential for prevention and treatment of various diseases. This paper summarized the research progress and its mechanism of the pharmacodynamics of mangiferin, in order to further in-depth study of mangiferin and provide a scientific basis for the development and utilization. |
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| Keywords: | mangiferin flavonoid prevention and treatment of diabetes mechanism of action |
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