婴幼儿轮状病毒性肠炎伴肠外感染的临床分析

目的分析轮状病毒性肠炎合并肠外感染的发生状况。方法对2010年9月-2011年1月共收治的72例轮状病毒性肠炎住院患儿采用酶联免疫吸附试验的方法检测粪便轮状病毒抗原,阳性者72例入观察组,阴性者32例入对照组,观察比较两组肝脏、心肌、呼吸及神经系统功能损害及表现。结果轮状病毒性肠炎可以导致肠道外感染而引起肝脏、心肌、呼吸及神经系统功能损害,表现为观察组患儿丙氨酸氨基转移酶（ALT）,天冬氨酸转移酶（AST）,肌酸激酶（CK）,肌酸激酶同工酶（CK-MB）活性均明显高于对照组（P〈0.05）差异有显著性。结论轮状病毒性肠炎常合并肠道外感染,以呼吸系统最常见,其次为肝脏、心肌及神经系统。损害大多常不严重,症状轻、恢复快,偶有重症病例,应早发现并及时给予保护措施,避免后遗症的发生。

Clinical Analysis of Infantile Rotavirus Enteritis Complicated by Extraintestinal Infections

【Objective】 To analyze the complications of rotavirus enteritis complicated by extraintestinal infections.【Methods】 Stool specimens were detected for rotavirus using ELISA in seventy-two infants with rotavirus enteritis who were treated in the First People＇s Hospital of Bengbu between September 2010 and January 2011.The seventy-two patients tested positive belonged to the observation group.And eighteen infants tested negative were recruited to the normal control group.Observe and compare the functional lesion and clinical manifestations of liver,myocardium,respiratory and nervous system in the two groups.【Results】 Rotavirus enteritis can lead to extraintestinal infections which caused the functional lesion of liver,myocardium,respiratory and nervous system.They were manifested that the activity of ALT,AST,CK,CK-mB were higher in observation group than that in normal control group（p0.05）,and their difference was significant.【Conclusion】 Rotavirus enteritis may be frequently complicated by extraintestinal infections which get liver,myocardium,respiratory and nervous system involved.Respiratory system was specially the most commonly infected.Their functional lesions are often not severe,the symptoms are not serious and they recuperate quickly,which consequently should be detected as early as possible and protection measures also should be taken to avoid sequelaes.