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牛磺酸对大鼠培养心肌细胞钙转运功能的作用
引用本文:董志超,马宏坤,吴玉华,孙辉,于波,张烁,关振中.牛磺酸对大鼠培养心肌细胞钙转运功能的作用[J].中国地方病学杂志,1998(6).
作者姓名:董志超  马宏坤  吴玉华  孙辉  于波  张烁  关振中
作者单位:哈尔滨医科大学附属第二医院,哈医大教务处
摘    要:以大鼠培养心肌细胞的脂质过氧化损伤模型,采用45Ca示踪技术,直接进行心肌肌浆网、线粒体钙转运功能的测定,同时观察牛磺酸对心肌过氧化损伤的保护作用。结果表明,牛磺酸能显著改善心肌肌浆网、线粒体钙转运功能,对心肌细胞具有保护作用

关 键 词:牛磺酸  心肌  细胞培养  

Effects of taurine on Ca 2 transportation of cultured myocardial cell in rats
Dong Zhichao,Ma Hongkun,Wu Yuhua,et al.Effects of taurine on Ca 2 transportation of cultured myocardial cell in rats[J].Chinese Jouranl of Endemiology,1998(6).
Authors:Dong Zhichao  Ma Hongkun  Wu Yuhua  
Institution:Dong Zhichao,Ma Hongkun,Wu Yuhua,et al Department of Cardiology,Second Affiliated Hospital,Harbin Medical University,Harbin 150086
Abstract:In order to observe the effects of taurine on Ca 2 transport by cardiac sarcoplasmic reticulum(SR) and mitochondria (Mit) in rats,the model of lipid peroxide injury in cultured rat beating heart cell was used.Myocardial SR and Mit isolated by discontinuous sucrose centrifugation were used for assay of Ca 2 uptake.The results showed that the pretreatment of taurine could significantly enhance the capacity of SR and Mit Ca 2 uptake.
Keywords:Taurine    Myocardium    Cell culture    Calcium
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