| 鼻咽癌原发瘤与颈转移瘤显微分光光度学和免疫组织化学的研究 |
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| 引用本文： | 林俊杰 郝兴培. 鼻咽癌原发瘤与颈转移瘤显微分光光度学和免疫组织化学的研究[J]. 癌症, 1998, 17(2): 90-92 |
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| 作者姓名： | 林俊杰 郝兴培 |
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| 作者单位： | 广东省中山市人民医院病理科，中山医科大学病理学教研室 |
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| 摘 要： | 在与原发瘤癌细胞比较下，探讨转移对癌细胞的生物学特性的影响。方法采用显微分光光度学和免疫组化，比较１０例鼻咽癌原发瘤和转移瘤中癌细胞的核核型和分化程度。结果：多数病例转移性鼻吕癌细胞的ＤＮＡ指数，单位面积ＤＮＡ指数和〉５．０ＣＤＮＡ百分率均降低，而在少数病例中却反而升高。
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| 关 键 词： | 鼻咽肿瘤 原发瘤 转移瘤 显微分光光度学 |
Study on the primary and metastatic tumours of nasopharyngeal carcinoma using microspectrometry and immunohistochemistry |
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| Abstract: | Purpose: To investigate the efects of metastasis on the biological characteristics of metastatic nasopharyngeal carcinoma (NPC) cells as compared with primary carcinoma cells. Method: To compare the karyotype and differentiation degree between metastatic and primary carcinoma cells in 10 NPC patients by use of microspectrometry and immunohistochemistry. Results: The DNA index, unit area DNA index and >5.0 C DNA percentage were decreased in majority of metastatic NPC cells while they might also be increased in some cases. Conclusion: The karyotype and differentiation degree detween primary and metastatic NPCs showed somewhat different because of their different residing microenvironments, namely, nasopharynx and lymph node. |
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| Keywords: | Nasopharyngeal neoplasm Primary tumour Metastases Microspectrometry Immunohistochemistry |
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