玄参中环烯醚萜类化合物的研究进展

环烯醚萜类化合物是玄参主要活性成分之一，根据化学结构将其分为环烯醚萜苷和非苷环烯醚萜两大类。并以环烯醚萜苷类化合物的生物合成过程为基础，推测脱羧环烯醚萜苷途径为玄参中环烯醚萜苷类主要生物合成途径。相关研究表明，哈巴苷、哈巴俄苷和桃叶珊瑚苷等成分在抗脑缺血、降血糖、保护心肌细胞等方面发挥重要作用，但仍有大部分环烯醚萜类成分的药理作用并不明晰。通过对玄参中环烯醚萜类化学成分的种类、生物合成技术以及药理作用的相关文献进行综述，为玄参环烯醚萜类化合物的开发应用提供参考。

Research advances on iridoids of Scrophularia ningpoensis

Iridoid compounds are one of the main active components of Xuanshen (Scrophulariae Radix), which were divided into two categories:iridoid glycosides and non-glucosylated iridoids according to their chemical structures. We speculated the possible biosynthesis pathway of iridoid glycosides in S. ningpoensis. It was speculated that the decarboxylated iridoid pathway was the main biosynthesis pathway of iridoid glycosides in S. ningpoensis. Relevant studies have shown that components such as harpagide, harpagoside, and aucubin play an important role in anti-cerebral ischemia, hypoglycemia, and the protection of cardiomyocytes. While the pharmacological effects of most iridoid glycosides are still not clear. This paper reviews the literature on types, biosynthesis techniques and pharmacological effects of iridoid compounds in S. ningpoensis, in order to provide a reference for its development and application.