| 急性脑梗死中风证型与血清胰岛素样生长因子-1和其结合蛋白-3水平的关系 |
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| 引用本文： | 俞征宙,刘楠,陈玉玲,林信富. 急性脑梗死中风证型与血清胰岛素样生长因子-1和其结合蛋白-3水平的关系[J]. 中国组织工程研究与临床康复, 2002, 6(23): 3616-3617 |
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| 作者姓名： | 俞征宙 刘楠 陈玉玲 林信富 |
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| 作者单位： | Second People's Hospital of Fujian Traditional Chinese Medicine，Union Hospital of Fujian Medical University，Union Hospital of Fujian Medical University，Second People's Hospital of Fujian Traditional Chinese Medicine Fujian350003，China，Fujian350003，China |
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| 基金项目： | sustentationfundfromFujianprovinceEducationalCommittee(No.JA02207). |
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| 摘 要： | ACI,adiseasewithhighmortalityrateandhighmutilationrate,isbelongingto“strokedisease”inTCMandcanbedividedintoAICandAIVbyTCM'ssyndromedifferentiation犤1犦.ThemechanismofACIcannotbeinterpretedcompletelybymodernmedicinehereto-fore.Recentstudiesindicatedthatinsulin-likegrowthfactor-1(IGF-1)couldinterferetheapoptosisofneuronincerebralischemia犤2犦.Inpresentstudy,wedetectedserumlevelofIGF-1andIGFBP-3in75patientsofACItoacquiretheessentialaboutACT'ssyn-dromessothatwecantreatACIbetterbyT…
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Research on the relationship between traditional Chinese medicine''''s syndrome and serum level of IGF-1 and IGFBP-3 in patients with acute cerebral infarction |
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| YU Zheng zhou,LIU Nan,CHEN Yu ling,LIN Xin fu. Research on the relationship between traditional Chinese medicine''''s syndrome and serum level of IGF-1 and IGFBP-3 in patients with acute cerebral infarction[J]. Journal of Clinical Rehabilitative Tissue Engineering Research, 2002, 6(23): 3616-3617 |
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| Authors: | YU Zheng zhou LIU Nan CHEN Yu ling LIN Xin fu |
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| Affiliation: | 1. Second People's Hospital of Fujian Traditional Chinese Medicine,Fujian 350003,China
2. Union Hospital of Fujian Medical University |
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| Abstract: | Objective To study the relationship between traditional Chinese medicine (TCM) syndrome and serum level of IGF 1 and IGFBP 3 in patients with acute cerebral infarction (ACI).Methods 75 patients of ACI were divided into two groups by TCM`s syndrome differentiation: apolexy involving the channels (AIC) and apolexy involving the viscera (AIV).Serum level of IGF 1 and IGFBP 3 was detected by ELISA di antibody clipping technique (DACT) and was compared with that of 30 normal controls.Results Serum level of IGF 1 and IGFBP 3 in AIC group and AIV group were significantly different from control groups;and differences between AIC group and AIV group were statistically significant.Serum level of IGF 1 and IGFBP 3 in all syndromes of AIC group and AIV group were remarkably lower than control group.Among them,syndrome of Yin deficiency of liver and kidney and sthenia liver yang and syndrome of blood stasis due to Qi deficiency had lower serum level of IGF 1 and IGFBP 3 than syndrome of empty and obstruction of channel.So did collapse syndrome and syndrome of mental disorder due to phlegm fire to syndrome of wind fire evil lucid orifices and block Yin syndrome.Conclusion There are to some extent correlation with TCM's Syndrome and serum level of IGF 1 and IGFBP 3 in patients with ACI. Serum level of IGF 1 and IGFBP 3 might be microcosmic referent markers of the damage of Qi and Yin by TCM`s syndrome differentiation. |
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| Keywords: | acute cerebral infarction TCM's syndrome IGF-1 IGFBP-3 |
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