| 低氮低热量肠外营养对胃癌患者全胃切除术后免疫功能的影响 |
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| 引用本文： | 王荣朝,陈焕年,王勍,尹勇.低氮低热量肠外营养对胃癌患者全胃切除术后免疫功能的影响[J].江苏医药,2011,37(7). |
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| 作者姓名： | 王荣朝 陈焕年 王勍 尹勇 |
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| 作者单位： | 苏州大学第三附属医院胃肠外科,常州市,213003 |
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| 摘 要： | 目的探讨低氮、低热量肠外营养对全胃切除术患者术后早期免疫功能的影响。方法将63例胃癌术后患者随机分为全胃肠外营养组(TPN,31例)和低氮、低热量肠外营养组(HHPN,32例)行肠外营养治疗。于术前1天、术后第1天和第8天分别检测外周血淋巴细胞计数、免疫球蛋白(IgG、IgMI、gA)、T淋巴细胞亚群(CD4、CD8、CD4/CD8)和人类白细胞抗原DR(HLA-DR)水平,比较两组的营养状况和免疫功能及术后感染性并发症等指标的差异。结果两组营养状况情况相仿。与TPN组比较,HHPN组术后第8天淋巴细胞计数I、gG、CD4、CD4/CD8和HLA-DR的表达显著升高(P<0.05),术后感染性并发症低。结论胃癌全胃切除术后使用低氮、低热量肠外营养更有利于患者术后免疫功能的恢复和减少感染性并发症。
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| 关 键 词： | 全胃切除术 胃肠外营养 免疫功能 |
Impact of hypocaloric and hyponitrogenic parenteral nutrition on immune of gastric cancer patients after total gastrectomy |
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| WANG Rongchao,CHEN Huannian,WANG Qing,et al..Impact of hypocaloric and hyponitrogenic parenteral nutrition on immune of gastric cancer patients after total gastrectomy[J].Jiangsu Medical Journal,2011,37(7). |
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| Authors: | WANG Rongchao CHEN Huannian WANG Qing |
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| Institution: | WANG Rongchao,CHEN Huannian,WANG Qing,et al.Department of Gastroenterology Surgery,Third Affiliated Hospital,Soochow University,Changzhou 213003,CHINA |
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| Abstract: | Objective To investigate the impact of hypocaloric and hyponitrogenic parenteral nutrition(group HHPN) on immune function of gastric cancer patients after total gastrectomy.Methods Sixty-three patients with gastric cancer were randomly and equally assigned into two groups of total parenteral nutrition(group TPN) and HHPN(group HHPN) for parenteral nutrition.Peripheral blood lymphocyte count,IgG,IgM,IgA,CD4,CD8,CD4/CD8 and human leukocyte antigen(HLA)-DR were examined one day before,on the 1st and 8th day af... |
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| Keywords: | Total gastrectomy Parenteral nutrition Immune function |
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