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2型糖尿病患者糖化血红蛋白与甲状腺激素水平分析
引用本文:赵进良,王洁,董永康,邵建伟,汤俊明. 2型糖尿病患者糖化血红蛋白与甲状腺激素水平分析[J]. 右江民族医学院学报, 2011, 33(1): 11-13. DOI: 10.3969/j.issn.1001-5817.2011.01.005
作者姓名:赵进良  王洁  董永康  邵建伟  汤俊明
作者单位:江苏省宜兴市人民医院,江苏宜兴,214200
摘    要:目的分析2型糖尿病患者糖化血红蛋白(HbA1c)与甲状腺激素水平的相关性,探讨长期血糖控制对糖尿病甲状腺功能影响的临床意义。方法采用化学发光法检测2型糖尿病及健康对照组游离三碘甲腺原氨酸(FT3)、游离甲状腺素(FT4)、超敏促甲状腺素(S-TSH),使用高效液相色谱仪分析HbA1c,同时分析受试者空腹血糖(FBG)。结果 2型糖尿病组FT3低于正常对照组(P<0.01),S-TSH高于对照组(P<0.01),FT4低于对照组,但差异无显著性(P>0.05);2型糖尿病患者FBG与HbA1c量成正相关(P<0.01),HbA1c与FT3浓度成负相关(P<0.05)。结论 2型糖尿病患者甲状腺激素水平紊乱增多且与长期高血糖相关。

关 键 词:2型糖尿病  甲状腺激素类  血红蛋白A,糖基化

The analysis of the correlation of the levels of glycosylated hemoglobin A1c and thyroid hormone in patients with type 2 diabetes mellitus
ZHAO Jin-liang,WANG Jie,DONG Yong-kang,SHAO Jian-wei,TANG Jun-ming. The analysis of the correlation of the levels of glycosylated hemoglobin A1c and thyroid hormone in patients with type 2 diabetes mellitus[J]. Journal of Youjiang Medical College For Nationalities, 2011, 33(1): 11-13. DOI: 10.3969/j.issn.1001-5817.2011.01.005
Authors:ZHAO Jin-liang  WANG Jie  DONG Yong-kang  SHAO Jian-wei  TANG Jun-ming
Affiliation:ZHAO Jin-liang,WANG Jie,DONG Yong-kang,SHAO Jian-wei,TANG Jun-ming (Yixing People's Hospital,Yixing,Jiangsu 214200,China)
Abstract:Objective To investigate the effects of long-term control of blood sugar in patients with type 2 diabetes mellitus by analyzing the correlation of the levels of glycosylated hemoglobinA1c(HbA1c) and thyroid hormone.Methods A chemiluminescence method was used to determine the serum concentrations of FT3,FT4 and S-TSH in patients with type 2 diabetes mellitus and in healthy control group.Meanwhile a High Performance Liquid Chromatography(HPLC) was used to analyze the glycosylated hemoglobinA1c(HbA1c) and the ...
Keywords:diabetes mellitus  type 2  thyroid hormones  hemoglobin A  glycosylated  
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