| 圆果甘草三萜成分的研究 |
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| 引用本文： | 梁鸿,张如意. 圆果甘草三萜成分的研究[J]. 药学学报, 1993, 28(2): 116-121 |
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| 作者姓名： | 梁鸿 张如意 |
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| 作者单位： | 北京医科大学药学院植化教研室，北京医科大学药学院植化教研室 北京 100083，北京 100083 |
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| 摘 要： | 从河南产圆果甘草(Glycyrrhiza squamulosa Franch.)的根中分离鉴定了五个三萜类化合物,即白桦酯酸(betulinic acid,S-8)、马其顿酸甲酯(methyl ester of macedonic acid,S-9)、黄豆醇B(soyasapoge nol B,S-10)、齐墩果13(18)-烯-22α-氯-3β,24-二醇(olean-13(18)-ene-22α-Cl-3β,24-diol,S-12)和圆果皂甙元(squasapogenol.S-11),均为首次从该植物中获得,其中S-10为首次在甘草属中发现,S-12为酸水解转变物,S-11是一个新的五环三萜类皂甙元,经光谱解析确定其结构为齐墩果-11,13(18)-二烯-3β,22β-二醇(olean-11,13(18)-diene-3β,22β-diol)。
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| 关 键 词： | 圆果甘草 三萜化合物 圆果皂甙元 |
| 收稿时间： | 1992-01-07 |
STUDIES ON THE TRITERPENOIDS FROM ROOTS OF GLYCYRRHIZA SQUAMULOSA FROANCH |
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| H Liang and RY Zhang. STUDIES ON THE TRITERPENOIDS FROM ROOTS OF GLYCYRRHIZA SQUAMULOSA FROANCH[J]. Acta pharmaceutica Sinica, 1993, 28(2): 116-121 |
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| Authors: | H Liang and RY Zhang |
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| Abstract: | A new triterpenoid, squasapogenol (S-11), was isolated from the hydrolytic products of dilute ethanol (10 %) extract of the roots of Glycyrrhiza squamulosa Franch. along with four known triterpenoids. The structure of S-11 was elucidated as olean-11,13 (18)-diene- 3β, 22β-diol on the basis of chemical and spectroscopic data. The four known compounds were identified as betulinic acid(S-8), methyl ester of macedonic acid(S-9), soyasapogenol B (S-10) and olean-13(18)-ene-22α-C1- 3β, 24-diol(S-12). |
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| Keywords: | Glycyrrhiza squamulosa Franch. Triterpenoid Squasapogenol |
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