慢性咳嗽病因诊断探讨

目的：探讨慢性咳嗽的病因。方法：采用慢性咳嗽解剖学诊断程序，对96例持续咳嗽8周以上的患者进行病因初步诊断，并通过针对性治疗证实。结果：在96例慢性咳嗽患者中，96．9％（93／96）的病因得到明确，其中鼻后滴漏综合征（postnasal drip syndrome，PNDS）46．9％（45／96），咳嗽变异型哮喘（cough variant asthma，CVA）42．7％（41／96），胃食管反流性疾病（gastroesophageal reflux disease，GERD）7．3％（7／96），病因未明3．1％（3／96）。针对病因特异性治疗，96．9％（93／96）患者的咳嗽症状消失或显著改善。结论：PNDS、CVA是慢性咳嗽的常见原因；试验性病因治疗有效是确诊病因的重要环节。

Etiological Diagnosis of Chronic Cough

Objective: To investigate the cause of chronic cough. Methods: The causes of 96 patients with consecutive cough for more than eight weeks were primarily evaluated with an anatomic diagnostic protocol and then determined by the specific therapy.Results: The causes of cough was determined in 93 of 96(96.9%) patients.Cough was due to postnasal drip syndrome in 45(46.9%) patients,cough variant asthma in 41(42.7%) patients,gastroesophageal reflux disease in 7(7.3%)patients.After active management based on the diagonosis,cough improved in 93 patients(96.9%).Conclusions: PNDS and CVA were important causes of chronic cough.A positive response to the specitic theraphy was essential to a definite diagnosis.