| 白介素8，白介素10联检在2型糖尿病肾病患者中的临床意义 |
| |
| 引用本文： | 肖憬,詹翔,桑圣刚,陈慧. 白介素8，白介素10联检在2型糖尿病肾病患者中的临床意义[J]. 现代保健, 2013, 0(12): 121-122 |
| |
| 作者姓名： | 肖憬 詹翔 桑圣刚 陈慧 |
| |
| 作者单位： | [1]武警甘肃总队医院,甘肃兰州730000 [2]海南医学院附属医院 ,甘肃兰州730000 [3]兰州大学第二医院,甘肃兰州730000 |
| |
| 摘 要： | 目的：探讨血清白细胞介素8、白细胞介素10水平的变化在糖尿病肾病发生、发展中的作用。方法：根据24h尿微量白蛋白排泄率对2型DN患者分组，观察血清IL-8、1L-10水平的改变。结果：糖尿病3组的IL-8、IL-10水平均明显高于正常对照组，随糖尿病肾病的严重程度增加而增加，且与及血肌酐呈正相关。结论：检测血清IL-8、IL-10水平的变化可以作为临床观察DN病情及判断DM预后的参考指标。
|
| 关 键 词： | 糖尿病肾病 白介素-8 白介素-10 尿微量白蛋白排泄率 |
Clinical Significance of Combined Detection of Serum IL-8 and IL-10 Levels for Diagnosis of Type 2 Diabetic Nephropathy |
| |
| Affiliation: | XIAO Jing, ZHAN Xiang, SANG Sheng-gang, et al(Medical Innovation of China) |
| |
| Abstract: | Objective： To investigate the significance of changes of serum IL-8 and IL-10 levels in the development of type 2 diabetic nephrosis. Method： The diabetic patients fell into three groups.Serum IL-8 and IL-10 levels were measured in type 2 diabetic patients and controls.Result： Serum levels of IL-8 and IL-10 were significantly higher in type 2 diabetes patients than those in controls and they increased in different stages of DN patients. There were positive correlations of serum IL-8, IL-10 with the concentration of Cr and UAER.Conclusion： Determination of serum IL-8 and IL-10 levels might be helpful for detection of diabetic nephropathy and monitoring the progress of the disease process. |
| |
| Keywords: | Diabetic nephropathy Interleukin-8 Interleukin-10 Urine albumin excretion rate |
| 本文献已被 维普 等数据库收录！ |
