颈动脉硬化和心血管危险因素与女性冠心病的相关性及诊断价值

目的探讨颈动脉硬化和心血管危险因素与女性冠心病的相关性及其在女性冠心病诊断中的价值。方法回顾分析因胸痛拟诊冠心病（CAD）入院的243例女性患者。记录高血压、糖尿病病史,行颈动脉彩超检查,冠脉造影,记录入院时收缩压、血脂、空腹血糖水平。分析颈动脉硬化积分及心血管危险因素与冠心病的相关性,及对冠心病的预测价值。结果对于女性胸痛患者来说,传统心血管危险因素中年龄、高血压病史或收缩压升高、糖尿病病史或空腹血糖升高、高密度脂蛋白降低与冠脉病变相关。颈动脉硬化积分、心血管危险因子数目均与冠脉病变相关且对冠脉病变有着相似的预测价值。颈动脉硬化积分的评定增加了心血管危险因子对患者冠脉是否有病变的预测价值。结论颈动脉硬化积分和心血管危险因子均与冠脉病变相关,同样可以用来评价女性胸痛患者冠脉是否有病变,综合心血管危险因子和颈动脉硬化积分,能提高心血管危险因子对冠脉病变的预测价值。

Correlations of carotid atherosclerotic and cardiovascular risk factor''s diagnostic with female coronary artery disease and their diagnostic values

Objective To explore the correlations of carotid atherosclertic and cardiovascular risk factor's diagnostic with female coronary artery disease(CAD)and their diagnostic values.Method We retrospectively analyzed the clinical data of 223 patients with chest pain and suspected CAD.History of hypertension and diabetes mellitus were documented,carotid ultrasonic examination and coronary angiography were performed,systolic blood pressure,lipid,fasting plasma glucose on admission were documented.We evaluated atherosclerotic plaque score and cardiovascular risk factors and its correlation to coronary disease and their predicting value.Results We found:in female with chest pain,cardiovascular risk factor includes hypertension or having higher systolic blood pressure,diabetes mellitus or having higher fasting plasma glucose,lower HDL,older age correlated of coronary heart disease.Compared with non-CAD,the female patients with CAD had much more cardiovascular risk factor and more serious carotid atherosclerotic.The carotid atherosclerotic plaque score was of the same importance as commonly used risk factors in the prediction of coronary heart disease.Relative to the other easily obtainable and established risk factors,it does not add substantially when used as a screening tool to discriminate subjects with high and low risk of coronary heart disease.Conclusion The carotid atherosclerotic plaque score and cardiovascular risk factor correlate with coronary heart disease.The carotid atherosclerotic plaque score is of the same importance as commonly used risk factors in the prediction of coronary heart disease.Compared with the other easily obtainable and established risk factors,it does not add substantially predicting value when used as a screening tool to discriminate subjects with high and low risk of coronary heart disease.