Ex Vivo Imaging of Pancreatic Beta Cells using a Radiolabeled GLP-1 Receptor Agonist期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Ex Vivo Imaging of Pancreatic Beta Cells using a Radiolabeled GLP-1 Receptor Agonist

Authors:	Brett M. Connolly Amy Vanko Paul McQuade Ilonka Guenther Xiangjun Meng Daniel Rubins Rikki Waterhouse Richard Hargreaves Cyrille Sur Eric Hostetler

Affiliation:	(1) Department of Imaging, Merck Research Laboratories, West Point, PA 19486, USA;(2) Department of Neuroscience, Merck Research Laboratories, West Point, PA 19486, USA;(3) Present address: Maccine Pte Ltd, Singapore, Singapore;(4) Present address: Abbott Laboratories, Abbott Park, North Chicago, IL, USA

Abstract:	Purpose The purpose of this study was to evaluate the binding specificity of the radiolabeled glucagon-like peptide 1 receptor (GLP-1R) agonist (Lys⁴⁰(DOTA)NH₂)Exendin-4 in the pancreas using a combination of ex vivo autoradiography and immunohistochemistry.

Keywords:
本文献已被 SpringerLink 等数据库收录！