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Positive serological tests for syphilis and administration of intravenous immunoglobulin
Authors:Constable S A  Parry C M  Enevoldson T P  Bradley M
Affiliation:Department of Pharmacology and Therapeutics, University of Liverpool, Ashton Street Medical School, Ashton Street, Liverpool L69 3GE, UK. s.constable@liverpool.ac.uk
Abstract:
We report the case of a man who tested positive for syphilis following the intravenous administration of human normal immunoglobulin as part of the treatment of Guillain-Barré syndrome. The chronology of the testing suggested the passive acquisition of treponemal antibody. This phenomenon is not widely documented in the medical literature, but is a theoretical risk of treatment, and serves as a reminder to be cautious in the interpretation of such serological tests.
Keywords:intravenous immunoglobulin   syphilis   serological tests
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