颅颈交界区畸形寰枢外侧关节生物力学稳定性的有限元分析

目的：利用有限元法分析颅颈交界区畸形（CJVM ）寰枢椎外侧关节生物力学变化。方法获取1例CJVM 枕骨和颈椎的CT扫描图像，利用三维造型和有限元软件建立颅颈交界区的三维有限元模型。施加生理载荷和边界条件，通过比较该模型与正常模型活动度的差异结合临床观察经验，验证模型的有效性，同时分析寰枢椎外侧关节应力分布。结果建立几何精度较高和参数设定可靠的CJVM有限元模型，通过模型发现各节段的活动度与相关尸体实验和有限元模型数据的结果相比总体呈偏小趋势，与一般CJVM患者临床实际运动表现相符合。获得了不同生理状况下畸形有限元模型寰枢椎外侧关节面的应力分布情况，可以合理解释寰枢外侧关节结构变异及其在维持寰枢椎之间稳定的重要作用。结论 CJVM 患者寰枢外侧关节结构发生变异，其生物力学稳定性对于术前的诊断和术中治疗操作具有一定价值。

Biomechanical of lateral atlantoaxial articulation in craniocervical junction malformation:afinite element analysis

Objective To analyze the biomechanical changes of lateral atlantoaxial articulation by means of three‐dimensional fnite element models of craniocervical junction malformation(CJVM) .Methods CT scan images of 1 patients with CJVM were ob‐tained .The analytical model was constructed by advanced three‐dimension modeling and finite element softwares .A comparison of range of motion difference between the deformity model and normal model ,referring to the experience of clinical observation ,was used to verify the validity of the model .Applying respectively the same loads and boundary conditions on finite element model .The effectiveness was verified by contrastive analysis of the variation in lateral atlantoaxial joint stresses .Results The finite CJVM ele‐ment model with high geometric accuracyand reliable parameter had built .Compared to the results of cadaver test and finite element model based in normal cranio‐cervical junction ,the segment mobility coincides with the actual clinical performance in patients .The stress distribution the lateral junction between atlas and axis of can be reasonably explained the deformation of lateral atlanto‐axial joint structure and its important role in remaining stable between atlantoaxial vertebraeunder different physiological conditions .Con‐clusion The structure of lateral atlantoaxial joint changes in patients of CJVM ,the biomechanical stability for preoperative diagno‐sis and intraoperative treatment operation has a certain value .