不育门诊男性精液质量及影响因素研究

目的：了解浙江南部地区不育门诊男性精液质量及危险因素。方法对浙南地区不育门诊的3017名男性精液进行检测，分析影响精液质量的因素。按精液质量分组，用全模型计算方程进行统计分析。结果精液质量参数的中位数：体积2.5 mL，密度76＆#215;106/mL，精子总数160＆#215;106，前向运动精子50.0％，总活率62.0％，正常形态6.9％。精液常规参数全部符合WHO标准的仅占32.90％。禁欲时间与精液体积、精子密度及总数呈正相关（P＜0.01）。单因素分析提示吸烟、接触环境污染物及肥胖对精液质量可能造成不良影响，但多因素分析差异均无统计学意义（P＞0.05）。结论浙南地区不育门诊部分男性精液质量低于WHO标准。地区差别、生活方式及环境因素可能造成精液质量的变化有待进一步研究。

A Cross-sectional Study on the Semen Quality and Potential Risk Factors in Males Attending Infertility Clinic in South Zhejiang

Objective： To explore the semen quality and potential risk factors of males from the infertility clinic in south area of Zhejiang.Methods A cross-sectional study was conducted to evaluate the semen quality and risk factors in 3 01 7 males attending infertility clinic in south Zhejiang.Subjects were grouped by semen quality.The generalized linear models were used to analyze the data.Results Medians of semen parameters were 2.5 ml for volume,76 ＆#215;1 06 per ml for semen concentration,1 60 ＆#215;1 06 for total sperm count,50.0%for sperm progressive motility,62.0%for total motility,and 6.9%for normal morphology.Only 32.9% of semen samples had normal semen parameters according to WHO criteria. Abstinence duration was significantly positive associated with semen volume,concentration,and total sperm count （P＆lt;0.01 ）.Single factor analysis showed that smoking,contacts of environmental pollutants,and obesity had slight detrimental effects on sperm quality.However,there were no significant differences by multiple factor analysis （P ＆gt;0.05 ）. Conclusion A sizable proportion of semen quality from males attending infertility clinic in south Zhejiang are low according to WHO criteria.The difference of area,life styles and environmental factors may cause the change of semen quality and that need to be further studied.