联合腹腔内和静脉路化疗治疗晚期消化系癌的临床研究

目的研究联合腹腔内和静脉路化疗治疗晚期消化系癌的疗效和毒性。方法先腹腔内化疗，每周１次，共２次，继予静脉路化疗２周，再予腹腔内化疗２周，６周为１疗程，观察治疗效果和毒性。结果４１例中２例ＣＲ，２４例ＰＲ，有效率６８４％，症状均得到改善。结论该治疗对晚期无腹水消化系癌是有效的，毒副作用轻，可作为一种常规治疗。

Clinical Study of Intraperitoneal Combined With IntravEnous Adminstration Treatment For Advanced-Stage Cancer In Digestive System

Objective To study the effects and toxicities of intraperitoneal combined with intravenous adminstration treatment for advanced stage cancer in digestive system.Methods The patients were treated with peri chemotherapy once every week for two weeks followed by intravenous chemotherapy for two weeks.totalling six weeks as a course of treatment so as to observe the curative effect and the toxicities.Results Amony 41 cases there were two of complete remission and 24 of partial remission with a total effective rate of 63 4% all patients showed improved in their symptoms and signs.The toxicities mainly include scleroma at injection site pain in puncturing site.abdominal distension, lypoleucocytosis and mild digective tract reaciton.Conclosion This treatment is effective for advanced stage cancer without adbominal dropsy of the digestive system with mild toxicitives thus it can used as a routine treatment.