参环毛蚓脂类挥发性成分分析

为了分析参环毛蚓（Ｐｈｅｒｅｔｉｍａ ａｓｐｅｒｇｉｌｌｕｍ）的脂类成分，我们采用不同溶剂索氏提取法，从该药材得到三种组分，用ＧＣ－ＭＳ法进行测定，确定了３６种化合物的结构。在这三种组分中，乙醚组分中的１１种成分均为脂为，不饱和脂肪酸的含量最高，占２７．７０％，如油酸、亚油酸、花生四烯酸和花生三烯酸。丙酮组分的脂类成分８种，占３５．７５％，不饱和脂肪酸只有亚油酸一种；乙醇组分的脂类成分１３种，占７

Study on Lipids and Other Volatile Constituents in Pheretima aspergillum

To study chemical constituents in Pheretima aspergillum, three kinds of fractions were obtained from this drug by soxhlet extraction with different solvents, and the chemical structures of thirty-six volatile components were identified by means of GC-MS. The eleven in ether fraction were all lipids and the relative content of non-saturated fatty acid was the highest(27.70%) such as oleic acid, linoleic acid, arachidonic acid and eicosatrienoic acid; There were eight lipids in acetone fraction (35.75%), which included one kind of nonsaturated fatty acid (linoleic acid); There were thirteen lipids in ethanol fraction (72.09%), which non-saturated fatty acid has never been detected. This study has determined the lipid composition in Pheretima aspergillum, especially non-saturated fatty acid, and afforded chemical base to cardio-cerebro-vascular therapy.