参七汤对急性心肌梗死PCI术后患者心功能及炎性因子的影响

目的:观察参七汤对急性心肌梗死经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)术后患者心功能及炎性因子的影响.方法:选取2018年6月至2020年7月本院收治的急性心肌梗死PCI术后患者90例,随机分为对照组和观察组各45例.对照组采用常规西药治疗联合锻炼,观察组在对...

The Influence of Ginseng and Sanchi Decoction on Cardiac Function and Inflammatory Factors in Patients with Acute Myocardial Infarction After PCI

Objective:To observe the influence of Ginseng and Sanchi Decoction on cardiac function and inflammatory factors in patients with acute myocardial infarction after percutaneous coronary intervention(PCI).Methods:A total of 90 patients with acute myocardial infarction after PCI treated in our hospital from June 2018 to July 2020 were divided into the control group and the observation group,with 45 cases in each group.The control group was treated with conventional Western medicine combined with exercise,while the observation group was treated with Ginseng and Sanchi Decoction,one dose a day,decocted in water and taken separately in the morning and evening.Both groups were treated for 1 month.Results:After treatment,cardiac troponin T(CTnT),creatine kinase isoenzymes(Ck-MB)and D-dimer decreased,and left ventricular ejection fraction(LVFF)increased in the two groups,and there were significant differences compared with those before treatment(P<0.05);there were also significant differences between the two groups(P<0.05).After treatment,the levels of interleukin-6(IL-6),high-sensitivity C-reactive protein(hs-CRP)and endothelial cell specific molecule-1(ESM-1)decreased in the two groups,and there were significant differences compared with those before treatment(P<0.05);there were also significant differences between the two groups(P<0.05).After treatment,the levels of platelet count and platelet aggregation rate decreased in the two groups,and there were significant differences compared with those before treatment(P<0.05);there were also significant differences between the two groups(P<0.05).The incidence of major cardiovascular adverse events in the control group was 40.00%,and that in the observation group was 17.78%,and there was significant difference compared with that before treatment(P<0.05);there was also significant difference between the two groups(P<0.05).Conclusion:Ginseng and Sanchi Decoction can effectively promote the recovery of cardiac function,inhibit inflammatory reaction and reduce the incidence of adverse cardiac events after PCI.