| 恶性淋巴瘤患者凝血四项指标变化及意义 |
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| 引用本文： | 王红霞,江亚军.恶性淋巴瘤患者凝血四项指标变化及意义[J].医学综述,2009,15(23):3675-3676. |
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| 作者姓名： | 王红霞 江亚军 |
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| 作者单位： | 1. 连云港市第一人民医院病理科,江苏,连云港,222002
2. 连云港市第二人民医院血液科,江苏,连云港,222023 |
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| 摘 要： | 目的观察恶性淋巴瘤(ML)患者的凝血四项指标变化。方法应用磁珠法检测66例ML患者和20例健康体检者的凝血酶原时间(PT)、部分凝血活酶时间(APTT)、凝血酶时间(TT)和纤维蛋白原(FIB)水平。结果ML患者APTT、FIB水平显著高于对照组(P<0.05、P<0.01);Ⅲ期ML患者FIB水平高于对照组和Ⅱ期患者(P<0.05);Ⅳ期患者APTT、FIB水平均明显高于对照组和Ⅱ期患者(P<0.05、P<0.01)。结论ML患者常伴凝血指标异常,表现为高凝状态。
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| 关 键 词： | 恶性淋巴瘤 凝血指标 高凝状态 |
The Alteration of Coagulation Function in Patients with Malignant Lymphoma |
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| Institution: | WANG Hong-xia , JIANG Ya-jun. ( 1. Pathology Department ,the First People＇s Hospital of Lianyungang City, Lianyungang 222002, China 2. Blood Department, the Second People＇s Hospital of Lianyungang City, Lianyungang 222023, China ) |
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| Abstract: | Objective To observe the alteration of blood coagulation indicators in the patients with malignant lymphoma（ML）. Methods 66 patients with ML and 20 healthy subjects were recruited, and the levels of prothrombin time （ PT ）, activated partial thromboplastin time （ APTT ）, thrombin time （TT） and fibrinogen（FIB） in blood plasma were tested by magnetic bead method. Results The levels of APTT and FIB in ML patients were significant higher than those in controls（ P 〈0.05 and 〈0.01 respectively）. The FIB level in stage Ⅲ patients was higher than those in controls and stage Ⅱ patients（ P 〈 0.05 ）, and the levels of APTT and FIB in stage Ⅳ patients were significant higher than those in controls and stage Ⅱ patients（ P 〈 0.05and 〈 0.01 respectively）. Conclusion The ML patients usually accompany with abnormal coagulation function and hypereoagnlabale state. |
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| Keywords: | Malignant lymphoma Coagulation indicators Hypercoagnlabale state |
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