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| 依托泊苷单药治疗老年晚期进展性肺癌的疗效评价 | |
| 引用本文： | 王允,贾霖,高飞,况小红,韩建军. 依托泊苷单药治疗老年晚期进展性肺癌的疗效评价[J]. 川北医学院学报, 2009, 24(1): 29-30 |
| 作者姓名： | 王允 贾霖 高飞 况小红 韩建军 |
| 作者单位： | 绵阳市第三人民医院肿瘤科,四川,绵阳,621000;绵阳市第三人民医院肿瘤科,四川,绵阳,621000;绵阳市第三人民医院肿瘤科,四川,绵阳,621000;绵阳市第三人民医院肿瘤科,四川,绵阳,621000;绵阳市第三人民医院肿瘤科,四川,绵阳,621000 |
| 摘 要： | 目的评价依托泊苷单药治疗老年晚期进展性肺癌的疗效及不良反应。方法对36例老年晚期进展性肺癌病人采用依托泊苷单药口服,剂量25mg/m2,每日两次,连服20天,每30天为一周期。按WHO实体瘤疗效评价标准及毒副作用标准确定疗效及毒副作用。结果病人接受三周期化疗后,部分缓解占16.7%(6/36),稳定占27.8%(10/36),进展占55.6%(20/36)。毒副作用轻微。结论依托泊苷单药持续口服对老年晚期进展性肺癌病人获得较好的疗效,毒副作用轻微,易为病人接受。 |
| 关 键 词： | 依托泊苷 老年晚期进展性肺癌 疗效评价 |
Clinical Effect of Etoposide Mono-therapy in Elderly Patients with Advanced Lung Cancer |
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| WANG Yun,JIA Lin,GAO Fei,KUANG Xiao-hong,HAN Jian-jun. Clinical Effect of Etoposide Mono-therapy in Elderly Patients with Advanced Lung Cancer[J]. Journal of North Sichuan Medical College, 2009, 24(1): 29-30 | |
| Authors: | WANG Yun JIA Lin GAO Fei KUANG Xiao-hong HAN Jian-jun |
| Affiliation: | ( Department of Medical Oncology, The Third People＇s Hospital of Miangyang, Mianyang, Sichuan 621000) |
| Abstract: | Objective To evaluate the clinical effect and adverse reaction of etoposide mono-therapy in elderly patients with advanced lung cancer. Methods Thirty-six elderly patients with advanced lung cancer were treated with etoposide, 25mg/m^2 twice daily for 20 days in a therapy cycle with 30 days. The ctinical effect and adverse reaction were evaluated according to the WHO standard on solid tumor. Results After 3 therapy cycles, 6 cases achieved partial regression （PR） , 10 cases achieved stable disease （SD） and 20 cases had progressed disease （PD）. There were no severe adverse reactions. Conclusion Etoposide mono-thcrapy is an efficacious and safe regimen for elderly patients with advanced lung cancer. |
| Keywords: | Etoposide Advanced lung cancer Efficacy evaluation |
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