颈内动脉严重狭窄或闭塞患者的认知功能损害及睡眠障碍特点

目的 探讨颈内动脉严重狭窄或闭塞患者的认知功能损害及睡眠障碍特点.方法 选取2015年1月~2016年6月江门市中心医院就诊的颈内动脉严重狭窄或闭塞患者40例(病例组),纳入80例颈内动脉未出现狭窄的自愿者作为对照组,采用蒙特利尔认知评估量表(MoCA)、简易智力状况检查量表(MMSE)、匹兹堡睡眠质量指数量表(PSQI)对两组的认知功能、睡眠情况进行测量,并进行对比分析.结果 病例组患者的视空间结构与执行力、注意力、记忆功能、语言功能、抽象思维、命名、时间及地点定向功能及MoCA总分均低于对照组(P<0.05);病例组患者的定向能力、语言、记忆、回忆、计算能力及MMSE总分均低于对照组(P<0.05);病例组患者的入睡时间、睡眠效率、睡眠时间、睡眠质量、日间功能障碍及催眠药物、PSQI总分均高于对照组(P<0.05).结论 颈内动脉严重狭窄或闭塞患者存在认知功能损害及睡眠质量下降.

Characteristics of cognitive impairment and sleep disorders in patients with severe stenosis or occlusion of internal carotid artery

Objective To explore the characteristics of cognitive impairment and sleep disorders in patients with severe stenosis or occlusion of internal carotid artery.Methods Forty patients(case group) with severe internal carotid artery stenosis or occlusion were selected from January 2015 to June 2016 in Jiang-men City Central Hospital. Eighty patients with no stenosis of internal carotid artery were enrolled as control group. The Montreal Cognitive Assessment scale(MoCA), Mini Mental State Examination(MMSE) and Pittsburgh Sleep Quality Index scale(PSQI) were assessed to measure the cognitive function and sleep quality in two groups. Results Scores of visual space structure and execution, attention, memory, language, abstract thinking, name, time and place of directional function and MoCA score were lower in case group than that in control group (P<0.05). Scores of orientation ability, language, memory, memory, calculation ability and MMSE scores were lower in case group than that in control group(P<0.05). Scores of sleep time, sleep efficiency, sleep time, sleep quality, daytime dysfunction and hypnotic drugs, PSQI scores were higher in case group than that in con-trol group(P<0.05).Conclusions Patients with severe stenosis or occlusion of internal carotid artery have cognitive impairment and decreased sleep quality.