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血管紧张素转换酶抑制剂降低高血压患者心房颤动发生危险
引用本文:刘英明,卢才义,王浩,王志国,高连如. 血管紧张素转换酶抑制剂降低高血压患者心房颤动发生危险[J]. 临床荟萃, 2004, 19(11): 601-602
作者姓名:刘英明  卢才义  王浩  王志国  高连如
作者单位:1. 解放军总医院,老年心血管病研究所,北京,100853
2. 海军总医院,心内科,北京,100037
摘    要:
目的 研究血管紧张素转换酶抑制剂 (ACEI)对高血压患者发生心房颤动 (房颤 )危险的影响。方法 将高血压患者分为房颤组 (n =1 5 6 )和非房颤组 (n =1 5 6 ) ,对其服药情况进行回顾性调查。结果 房颤组服用ACEI者有 4 0例 (2 5 .6 % ) ,非房颤组服用ACEI者有 6 5例 (4 1 .7% ) ,两组相比差异具有统计学意义 (P<0 .0 1 ) ,服用ACEI的患者发生房颤的危险降低 (OR =0 .4 8)。结论 ACEI能够降低高血压患者房颤发生危险

关 键 词:血管紧张素转换酶抑制药 高血压 心房颤动 肾素-血管紧张素系统
文章编号:1004-583X(2004)11-0601-02

Risk of angiotensin converting enzyme inhibitors in decreasing atrial fibrillation of essential hypertension patients
LIU Ying ming ,LU Cai yi,WANG Hao,WANG Zhi guo,GAO Lian ru Institute of Geriatric Cardiology,General Hospital of PLA,Beijing ,China. Risk of angiotensin converting enzyme inhibitors in decreasing atrial fibrillation of essential hypertension patients[J]. Clinical Focus, 2004, 19(11): 601-602
Authors:LIU Ying ming   LU Cai yi  WANG Hao  WANG Zhi guo  GAO Lian ru Institute of Geriatric Cardiology  General Hospital of PLA  Beijing   China
Affiliation:LIU Ying ming *,LU Cai yi,WANG Hao,WANG Zhi guo,GAO Lian ru *Institute of Geriatric Cardiology,General Hospital of PLA,Beijing 100853,China
Abstract:
Objective To study the effect of angiotensin converting enzyme inhibitor(ACEI) on the risk of atrial fibrillation in essential hypertension patients.Methods Essential hypertension patients were divided into atrial fibrillation group(n=156) and no atrial fibrillaton group(n=156),history of taking antihypertensive drugs was retrospectively investigated. Results Forty patients taking ACEI in atrial fibrillation group( 25.6 %),sixty five patients taking ACEI in no atrial fibrillation group( 41.7 %) showed significant difference(P< 0.01 ), risk of atrial fibrillation decreased in patients taking ACEI (OR= 0.48 ). Conclusion ACEI decreases the risk of atrial fibrillation in essential hypertension patients.
Keywords:angitensin converting enzyme inhibitors  hypertension  atrial fibrillation  renin angiotensin system
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