蓝光滤过型非球面人工晶状体植入术后视觉质量的临床研究

目的观察行超声乳化白内障吸除联合植入蓝光滤过型非球面人工晶状体（HOYA PY-60AD）眼的术后视觉质量。设计前瞻性临床研究。研究对象57例（57眼）年龄相关性白内障患者。方法接受超声乳化白内障吸除术的年龄相关性白内障患者57例（57眼）按就诊顺序登记及随机表法将患者分为2组，术中分别植入非球面人工晶状体HOYAPY-60AD（29眼）和球面人工晶状体HOYA AF-1（UY）（28眼）。术后随访3个月。随访时进行一般眼科检查，包括视力、眼压、眼前节及眼底，并记录术后3个月时的裸眼视力（UCVA）、最佳矫正视力（BCVA）、低对比度视力（ETDRS低对比度视力表）、对比敏感度（OPTEC6500，明视、明视眩光、间视和间视眩光）并填写调查问卷（Catquest-9SF）。主要指标UCVA，BCVA，低对比度视力，对比敏感度和调查问卷分值。结果术后3个月，非球面组患者明视（400Lux）条件下5％对比度视力（0．35±0．13）及间视（30Lux）条件下5％（0．49±0．13）和25％（0．25±0．12）对比度视力均好于球面组，分别为（0．43±0．15）、（0．61±0．12）、（0．32±0．14），差异有统计学意义（P均≤0．05），间视及间视＋眩光条件下低中频（1．5c／d、3c/d、6c／d、12c/d）的对比敏感度非球面组均好于球面组，差异有统计学意义（P均40．05）。两组患者UCVA、BCVA及调查问卷分值均无统计学差异（P均≥0．05）。结论非球面人工晶状体能够提供较好的低对比度视力和暗环境下的对比敏感度，提示非球面人工晶状体能够提供较好的视觉质量。（眼科，2010，19：89-92）

Clinical study of the vilsual quality of eyes implanted with aspherical blue-light-filtering intraocular lenses

Objective To evaluate the vilsual quality of eyes implanted with aspherical blue-light-filtering intraocular lenses （IOLs）. Design Prospective clinical trial. Participants Fifty-seven eyes of 57 patients with age-related cataracts. Methods Patients were randomly divided into 2 groups according to random number table. Phacoemulsification and IOL implantation were applied to patients with aspherical IOLs （HOYA PY-60AD） in 29 eyes and spherical IOLs （HOYA AF-1） in 28 eyes, respectively. All patients were followed up for 3 months. General examinations including visual acuity, intraoeular pressure, anterior segment and fundus photography in the first two visits. Uncorrected visual acuity （UCVA）, best corrected visual acuity （BCVA）, contrast vision （ETDRS low contrast visual acuity chart）, contrast sensitivity （OPTEC6500 Visual founction analyzer） and questionnaire （Catquest-9SF score） were applied at the 3rd month post-operation. Main Outcome Measures UCVA, BCVA, low contrast visual acuity, contrast sensitivity and questionnaire. Results 5% contrast vision under photopic（aspherical/spherical： 0.35±0.13/0.43±0.15 ） and mesopic conditon（0.49±0.13/ 0.61±0.12）and 25% contrast vision under mesopic conditon（0.25±0.12/0.32±0.14） was significantly better in eyes with aspherical IOLs than in thoses with spherical IOLs（P〈0.05）. Higher contrast sensitivity values under mesopic and mesopic with glare conditions 0.5 c/d, 3 c/d, 6 c/d, 12 e/d） were also found in aspherical IOLs group （P〈0.05 in each condition）. UCVA, BCVA and questionnaire results were similar between groups. Conclusion The aspherical IOLs provided better low contrast vision and contrast sensitivity under mesopic conditions, thus improved the optical quality. （Ophthalmol CHN, 2010, 19： 89-92）