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TrkA在周围神经损伤后的表达
引用本文:尹方明,余国海,胡耀民,刘大庸,王国英,钟世镇. TrkA在周围神经损伤后的表达[J]. 第一军医大学分校学报, 1998, 0(1)
作者姓名:尹方明  余国海  胡耀民  刘大庸  王国英  钟世镇
作者单位:解放军广州医学高等专科学校外科学教研室 广州510315(尹方明,余国海),第一军医大学解剖学教研室 广州510515(胡耀民,刘大庸,王国英,钟世镇)
基金项目:国家自然科学基金资助课题,No.39470365
摘    要:
目的:确定Trk(Tyrosine kinase)A在损伤周围神经的表达分布。方法:切断大鼠坐骨神经再吻合后,不同时段上,取脊髓、脊神经节和吻合的神经段作LSAB免疫组化染色,光镜进行观察。结果:TrkA只在损伤的脊神经节感觉神经元胞体和坐骨神经呈免疫组化阳性反应。结论:TrkA只在损伤的脊神经节感觉神经元胞体和坐骨神经表达。

关 键 词:周围神经损伤  TrkA  表达

TrkA expression following rat peripheral nerve injury
Yin Fangmin,Yu Guohai,Hu Yaomin,Liu Dayong,Wang Guoying,Zhong Shizhen. TrkA expression following rat peripheral nerve injury[J]. Journal of Branch Campus of the First Military Medical University, 1998, 0(1)
Authors:Yin Fangmin  Yu Guohai  Hu Yaomin  Liu Dayong  Wang Guoying  Zhong Shizhen
Abstract:
Objective : Locate the site of TrkA expression following rat peripheral nerve injury. Method: Cut the night sciatic nerve of SD rat and anastomosed them, at different time after operation, removed out the spinal cord, dorsal root ganglia, nerve stump and stained with LSAB immunohistochemical method.Results: There were only positive immunore-actions in the operated sciatic nerve ( right)and the ipsilateral dorsal root ganglia. Conclusions : TrkA expresses only in the operated sciatic nerve (right)and the ipsilateral dorsal root ganglia.
Keywords:peripheral nerve injury TrkA expression
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