正电子发射型断层显像在结直肠癌肝转移诊断中的应用

目的 评价正电子发射型断层显像(PET)在结直肠癌术后肝转移诊断中的作用。方法 对18例怀疑结直肠癌术后肝转移的患者和3例怀疑其他疾病的患者进行PET检查，通过与CT比较及手术探查，评价PET在结直肠癌肝转移诊断中的作用。结果 怀疑术后肝转移的18例患者，经PET显像确诊17例，其中14例同时伴有肝脏以外的其他脏器转移(肺转移2例、腹壁转移2例、骨转移1例、腹腔淋巴结转移6例、纵隔淋巴结转移2例、锁骨上淋巴结转移1例)；PET诊断阴性的1例患者，随访1年后仍无瘤存活。3例怀疑其他疾病的患者经PET检查发现有结肠癌伴肝转移。结论 与CT相比，PET对结直肠癌术后肝脏及其他部位转移的敏感度更高，对术后肝转移患者是否选择再次手术具有更好的指导意义。

Application of positron emission tomography in diagnosis of liver metastases from colorectal cancer

Objective To evaluate the value of positron emission tomography (PET) in diagnosing liver metastases from colorectal cancer. Methods Eighteen patients suspected with liver metastases after resection of colorectal cancer and three patients suspected with other diseases were diagnosed by PET and CT before operation. The result of both diagnostic approaches was compared with the result of exploratory operation. Results Seventeen of 18 patients were confirmed as liver metastases after resection of colorectal cancer, in whom 14 patients had other synchronous metastases outside liver metastasis including lung metastasis (n=2), abdominal wall metastasis (n=2), bone metastasis (n=1), peritoneal cavity lymph nodes metastasis (n=6), mediastinal lymph nodes (n=2), virchow lymph nodes metastasis (n=1). One patient with negative PET diagnosis was still alive with cancer free after 1 year followed up. Three patients suspected with other diseases were also diagnosed as liver metastases from colorectal cancer by PET. Conclusion PET has higher sensitivity in diagnosing liver metastases or other synchronous metastases after resection of colorectal cancer, which suggests that PET can guide the determination of second operative surgery for liver metastases after resection of colorectal cancer.