检测麻疹IgM抗体对诊断麻疹的意义和麻疹IgM阳性病例的临床表现

分析了 1993～ 1998年 45 6例采集血标本的麻疹确诊病例和 83例采集双份血标本的麻疹确诊病例的麻疹IgM抗体阳性率。发病后 4～ 2 1天阳性率分别为 92 86%和 95 0 6% ,而发病后 1～ 3天和 2 2～ 42天的麻疹IgM阳性率显著较低。病例的同一份血清检测麻疹和风疹两种IgM抗体 ,说明麻疹阳性和风疹阳性互不干扰 ,各具特异性。分析 2 70份麻疹IgM阳性的病例临床表现 ,不同年龄组和有无免疫史的表现有极显著差别。检测麻疹IgM抗体具有高度特异性、敏感性和早期诊断的意义

The Diagnotic Significance of Measles IgM Antibody Detection by Capture ELISA and the Clinical Manifestations of Cases Showing Positive Measles IgM

Analyzing 456 confirmed measles cases and 83 two serum samples of them, the measles IgM positive rate in the period of fourth to twentieth day of disease onset was 92.86% and 95.06%, but that was much more lower at 1st-3rd day and 22th-42th day of the disease onset. Analyzing 270 measles cases with positive measles IgM, the clinical manifestations appeared significantly different between different age groups and different history of immunity. Detection of measles IgM antibody is proved to be a good method for measles early diagnosis with specificity, sensitivity and speediness.