太原地区内科住院患者军团菌抗体调查及医院感染军团菌病

用MAT及ELISA检测200例内科住院患者血清3种军团菌抗体。呼吸组Lp1抗体阳性率两种方法均高于正常人群及非呼吸组病人。Lb、Lj抗体阳性率(MAT法)住院病人高于正常人群,但呼吸组与非呼吸组间无显著差别。部分患者抗体滴度增长>4倍或持续阳性。一例临床表现、抗体检测及药物疗效显示可能为医院感染佐丹军团菌肺炎。作者强调重视医院感染军团菌病。

Prevalence of Antibodies to Legionella in Medical Care inpatients in Taiyuan and Nosocomial Legionellosis

Serum samples from 200 hospitalized medicalcare patients were examined for antibodies to 3 speciesof Legionella by MAT and ELISA. The positive ratesof LpI antibody of the patients with respiratory dis-eases tested by both methods were higher than those ofthe healthy population and the non-respiratory dis-ease group. The frequencies of antibody to Lb and Ljin patients tested by MAT were higher than those innormal population, but the differences between thetwo groups of patients were not significant. Some pa-tients had a fourfold or higher rise in antibody titers orthe titers kept positive in double serum samples. Theclinical features, antibody titers as well as the effect of specific treatment suggested that it was a case ofnosocomial pneumonia caused by Legionella iordanis.