刺络放血疗法治疗系统性硬化症临床观察

目的：观察刺络放血疗法治疗系统性硬化症的临床疗效。方法：选取系统性硬化症患者44倒，随机分为观察组和对照组各22例，对照组口服沙立度胺和醋酸泼尼松片；观察组在对照组口服西药的基础上每周行两次刺络放血疗法。结果：观察组痊愈5例，显效12例，有效4例，无效1例，总有效率为95．45％（95％CI=77．2％～99．9％）；对照组痊愈1例，显效10例，有效5例，无效6例，总有效率为72．73％（95％CI：49．8％～89．3％）；两组综合疗效比较（u=2．2530，P=0．0247），差异有显著性意义；治疗后，观察组较对照组齿距增加（P〈0．05）、指距减小（P〈0．05）、全身皮肤积分、关节压痛指数、血沉参数均下降（P〈0．01）。结论：在西药治疗的基础上配合刺络放血疗法治疗系统性硬化症的疗效优于单纯口服西药，其收益为OR=0．13（95％CI=0．01～1．16），NNT=4（95％CI=2．26～90．91）。

Clinical Observation of Therapy of Venesection for Blood-letting on Systemic Sclerosis

Objective:To observe the clinical effect of therapy of venesection for blood-letting on systemic sclerosis.Method:44 cases with systemic sclerosis were randomly divided into two groups,22 cases in each group.All the cases were treated by Thalidomide and prednisone acetate tablets.Then the ones in treatment group were treated with venesection for blood-letting,two times in a week.Result:In treatment group 5 cases were cured,12 ones excellent,4 ones effective,and 1 ones ineffective.The total effective rate wa...