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Rehabilitative intervention during and after pediatric hematopoietic stem cell transplantation: An analysis of the existing literature
Authors:Francesca Rossi  Monica Coppo  Giulia Zucchetti  Daniela Bazzano  Federica Ricci  Elena Vassallo  Francesca Nesi  Franca Fagioli
Affiliation:1. Rehabilitation Service, Public Health and Paediatric Sciences Department, A.O.U. Città della Salute e della Scienza–Regina Margherita Children Hospital, Turin, Italy;2. Degree Course of Neuro‐Psychomotor Therapy of Developmental Age, School of Medicine, University of Turin, Italy;3. Pediatric Oncohematology, Stem Cell Transplantation and Cell Therapy Division, A.O.U. Città della Salute e della Scienza–Regina Margherita Children Hospital, Turin, Italy;4. Public Health and Paediatric Sciences Department, A.O.U. Città della Salute e della Scienza–Regina Margherita Children Hospital, Turin, Italy
Abstract:Hematopoietic stem cell transplantation is a therapeutic strategy for several oncohematological diseases. It increases survival rates but leads to a high incidence of related effects. The objective of this paper was to examine the existing literature on physical exercise interventions among pediatric HSCT recipients to explore the most often utilized rehabilitative assessment and treatment tools. Studies published from 2002 to April 1, 2015 were selected: 10 studies were included. A previous literary review has shown that rehabilitation programs have a positive impact on quality of life. Our analysis identified some significant outcome variables and shared intervention areas.
Keywords:graft versus host disease  neurotoxicity of therapy  pediatric oncology  quality of Life  stem cell transplantation  supportive care
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