| ~(11)C-MET PET/CT在脑肿瘤诊断中的初步应用 |
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| 引用本文： | 赵春雷,陈自谦,李天然,钱根年,杨忠东,王楷堂,李铭山.~(11)C-MET PET/CT在脑肿瘤诊断中的初步应用[J].福州总医院学报,2008,15(3). |
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| 作者姓名： | 赵春雷 陈自谦 李天然 钱根年 杨忠东 王楷堂 李铭山 |
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| 作者单位： | 福州总院医学影像中心PET-CT室; |
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| 摘 要： | 目的:初步评价11C-MET PET/CT脑显像临床应用价值。方法:研究对象为5例健康志愿者和36例脑部肿瘤患者,健康志愿者行11C-MET PET/CT脑显像,并作为对照组,36例脑部肿瘤患者中19例同时行11C-MET及18F-FDG PET/CT显像,17例仅行11C-MET PET/CT显像;结合健康对照组图像,对本组36例脑部肿瘤患者11C-MET PET/CT脑显像进行分析,并对同时进行18F-FDG PET显像者进行配对比较。结果:所有患者中,11C-MET PET/CT显像阳性者30例,T/B均值为1.72±0.39,18F-FDG PET/CT显像阳性者9例,T/B均值为1.49±0.13。19例患者接受11C-METPET/CT及18F-FDG PET/CT脑显像,T/B均值分别为1.64±0.49及1.16±0.36(t=3.33,P<0.01)。11C-METPET/CT显像诊断脑肿瘤初诊患者灵敏度、特异性及准确性均为100%,其诊断脑肿瘤复发的灵敏度、特异性及准确性分别为94.7%(18/19)、100%(5/5)、95.8%(23/24)。结论:单独行11C-MET PET/CT脑...
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| 关 键 词： | PET／CT显像 脑肿瘤诊断 MET GPET显像 健康志愿者 健康对照组 肿瘤患者 临床应用价值 |
Initial clinical application of ~(11)C-MET PET/CT brain tumor imaging |
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| Zhao chun-lei,Li tian-ran,Chen zi-qian,Qian gen-nian,Yang zhong-dong,Wang kai-tang,Chen shu.Initial clinical application of ~(11)C-MET PET/CT brain tumor imaging[J].Journal of Fuzhou Genenal Hospital,2008,15(3). |
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| Authors: | Zhao chun-lei Li tian-ran Chen zi-qian Qian gen-nian Yang zhong-dong Wang kai-tang Chen shu |
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| Institution: | Zhao chun-lei1,Li tian-ran1,Chen zi-qian1,Qian gen-nian1,Yang zhong-dong1,Wang kai-tang1,Chen shu2(1. PET/CT Center,2. Department of Neurosurgery,Fuzhou General Hospital,Nanjing Military Comm, of PLA,Fuzhou 350025,China) |
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| Abstract: | Objective:To evaluate the diagnosis value of 11C-MET PET/CT brain tumor imaging initially. Method:5 healthy volunteer and 36 brain tumor patients were involved in this study. 5 healthy volunteer underwent 11C-MET PET/CT brain imaging and were set as control group. In thoses 36 brain tumor patients,19 patients underwent both11C-MET and 18F-FDG PET/CT,17 patients only underwent11C-MET PET/CT brain imaging. We analysised the 3611C-MET PET/CT imaging and compared those with control group and those 19 patients w... |
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