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| 应用单克隆抗体诊断泌尿系统肿瘤骨髓内的微转移 | |
| 引用本文： | 李胜文 Leiss.,J. 应用单克隆抗体诊断泌尿系统肿瘤骨髓内的微转移[J]. 中华泌尿外科杂志, 1995, 16(2): 86-88 |
| 作者姓名： | 李胜文 Leiss. J |
| 作者单位： | 白求恩医科大学第三临床学院泌尿外科 |
| 摘 要： | 以抗细胞角质蛋白－１８（ＣＫ－１８）单克隆抗体为标记抗体，采用免疫细胞化学染色方法研究了６４例泌尿系统肿瘤在骨髓中的微转移，发现２８．１％的病人有骨髓微小转移。此方法可以将癌细胞染成红色，显微镜下很容易与正常骨髓细胞相区别。我们认为此方法敏感、准确、实用，同一种方法可用于不同癌症患者的检查。 |
| 关 键 词： | 单克隆抗体 泌尿系肿瘤 骨髓 转移 |
Detection of bone marrow micrometastases of urological carcinoma using monoclonal antibody |
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| Li Shengwen,Leissner J,Voges G,et al.. Detection of bone marrow micrometastases of urological carcinoma using monoclonal antibody[J]. Chinese Journal of Urology, 1995, 16(2): 86-88 | |
| Authors: | Li Shengwen Leissner J Voges G et al. |
| Abstract: | Anti-cytokeratin-18 monoclonal antibody was used to detect bone marrow micrometastases in 64 patients with bladder carcinoma,prostate carcinoma or renal carcinoma.Cytokeratin-18 postitive cells in bone marrow were found in 28.1% of the patients,the tumour cells being stained red and being easily differentiated from the normal hematopoietic cells.The technique is sensitive and accurate to detect bone marrow micrometastases of urological carcinoma. |
| Keywords: | Monoclonal antibody Urologic neoplasms Micrometastasis |
| 本文献已被 CNKI 维普 等数据库收录！ | |