超声造影与常规超声鉴别诊断附件区肿块的比较研究

目的 比较常规超声和实时超声造影对附件区肿块的鉴别诊断性能.方法 对137例附件区肿块行常规超声和实时超声造影检查.两位超声医师(受试者)对检查结果独立作出诊断,用ROC曲线评估常规超声和实时超声造影对附件区肿块的鉴别诊断性能,Kappa值评估受试者之间的一致性.结果 ROC曲线显示两位受试者得到的曲线下面积:常规超声分别为0.731和0.738,超声造影分别为0.891和0.903(P＜0.01).超声造影能明显提高判别病变良恶性的准确性.受试者之间的一致性超声造影高于常规超声,κ值分别为0.893和0.681.两位受试者对附件区病变的诊断正确率常规超声分别为73.2％和74.2％,超声造影分别为90.7％和91.2％(均P＜0.01).结论 实时超声造影可明显提高超声对附件区病变的鉴别诊断能力.

Comparison between baseline and contrast-enhanced ultrasound in characterization of adnexal masses

Objective To assess the diagnostic performance of contrast-enhanced ultrasound(CEUS)in characterization of adnexal masses in comparison with baseline ultrasound.Methods One hundred and thirty-seven masses were examined by CEUS and baseline ultrasound.Two independent investigators reviewed the images before and after contrast agent administration.The diagnostic performances were evaluated using receiver operating characteristic (ROC) analysis and the interobserver agreement was analyzed.Results After review of CEUS,ROC analysis revealed significant improvement in differentiating between malignant and benign pelvic masses that the areas under the ROC curve were 0.731 and 0.738 at baseline ultrasound versus 0.891 and 0.903 at CEUS ( P ＜0.01 ).The accuracy for both investigators also improved significantly after reviewing CEUS.A better interobserver agreement was achieved after reviewing of CEUS (g =0.681 at baseline ultrasound versus κ =0.893 at CEUS) and a better result of specific diagnosis was obtained (73.2％ and 74.2％ at baseline ultrasound versus 90.7％ and 91.2％ at CEUS)(all P ＜ 0.01 ).Conclusions Real-time CEUS improves the diagnostic performance in adnexal masses for discrimination between malignancy and benignity and improves the capability in specific diagnosis compared with baseline ultrasound.