帕珠沙星的药理与临床应用

帕珠沙星为广谱抗菌药，与头孢他啶、亚胺培南、庆大霉素相比，对耐甲氧西林金黄色葡萄球菌（MRSA）的抗菌活性突出，抗革兰阴性菌的活性优于头孢他啶、亚胺培南和庆大霉素，与环丙沙星相当。对部分厌氧菌也有较强的抗菌活性。临床研究表明，对呼吸道感染、复杂尿路感染、外科感染、妇科感染等有较高的疗效，不良反应较轻。帕珠沙星抗菌谱广、临床疗效高、不良反应少，有较好的临床应用前景。

Pharmaceutical Mechanism and Clinical Application of Pazufloxacin

Pazufloxacin is a wide spectrum antibiotics with advance of MRSA compared with ceftazidime,imipenem gentamycin and as same as ceftazidime,imipenem and gentamycin in gram negative bacteria.It is stronger than the ciprofloxacin for anaerobe.There was efficient curative effect in clinic in respiratory,urinary,surgery and obstetrics infection with less side effect.It might be widely use in clinic for wide spectrum,high effect and less side effect.