| 镉对大鼠肠粘膜中三价运铁蛋白形成的影响 |
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| 引用本文： | 陈炳卿,菅原直毅,菅原千枝子.镉对大鼠肠粘膜中三价运铁蛋白形成的影响[J].营养学报,1990(2). |
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| 作者姓名： | 陈炳卿 菅原直毅 菅原千枝子 |
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| 作者单位： | 哈尔滨医科大学公共卫生学院营养与食品卫生教研室，日本札幌医科大学公众卫生教室，日本札幌医科大学公众卫生教室 哈尔滨 150001，北海道，北海道 |
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| 摘 要： | 通过经口投给100ppm氯化镉与不投给镉的两组Wistar雄性大鼠研究镉对大鼠肠粘膜中三价运铁蛋白形成的影响。结果表明,镉可降低脏器中贮藏铁的含量,可阻止铁进入肠全粘膜中,镉引起动物铁不足与其枯膜中铁蛋白及其它未知蛋白结合的关系应给以重新评价,而在体外试验中,即使给于高浓度氯化镉,对前运铁蛋白转为运铁蛋白也仅仅表现轻微的抑制作用。
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| 关 键 词： | 镉 运铁蛋白 铁蛋白 |
EFFECT OF CADMIUM ON Fe~(3 )-TRANSFERRIN IN RAT INTESTINAL MUCOSA |
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| Chen Bingqing,Jian Yuan Zhi Yi,Jian Yuan Qian Zhi Zi.EFFECT OF CADMIUM ON Fe~(3 )-TRANSFERRIN IN RAT INTESTINAL MUCOSA[J].Acta Nutrimenta Sinica,1990(2). |
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| Authors: | Chen Bingqing Jian Yuan Zhi Yi Jian Yuan Qian Zhi Zi |
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| Abstract: | Two groups of male Wistar rats received 100 ppm cadmium chloride solution and tap water respectively ad libitum. The result indicated that cadmium not only decreased iron stored in organs hut also blocked iron getting into intestinal mucosa. The relations between animal iron deficiency induced by cadmium and ferritin, unknown binding-ferritin in intestinal mucosa should be reassessed. In vitro, even under the condition of high concentration of cadmium chloride, the process of pretransferrin changing to transferrin was only blocked slightly. |
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| Keywords: | cadmium transferrin ferritin |
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