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| 慢性肾血管性高血压大鼠脑细胞膜游离脂肪酸水平变化 | |
| 引用本文： | 鲁佑瑜,秦震. 慢性肾血管性高血压大鼠脑细胞膜游离脂肪酸水平变化[J]. 中国临床神经科学, 1997, 5(3): 145-147 |
| 作者姓名： | 鲁佑瑜 秦震 |
| 作者单位： | 上海市第一人民医院神经科 200080(鲁佑瑜)，上海医科大学华山医院 200010(秦震)，上海医科大学药学仪器分析中心 200032(莫谷强) |
| 摘 要： | 采用SD大鼠慢性肾血管性高血压模型,气-液色谱法测定高血压组(n=8)、对照组(n=9)脑细胞膜游离脂肪酸(Free Fatty Acid,FFA)单组分水平。结果显示高血压组脑细胞膜FFA组份中C20:4、C22:6水平显著高于对照组(P |
| 关 键 词： | 大鼠 高血压 脂肪酸 |
Brain Cell Membrane FFAs Contents of Chronic Renovascular Hypertension in Rats |
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| Lu You-Yu,Qin Zhen,Mo Guqiang. Brain Cell Membrane FFAs Contents of Chronic Renovascular Hypertension in Rats[J]. Chinese Journal of Clinical Neurosciences, 1997, 5(3): 145-147 | |
| Authors: | Lu You-Yu Qin Zhen Mo Guqiang |
| Affiliation: | Lu You-Yu,Qin Zhen,Mo GuqiangDepartment of Neurology .Shanghai First People's Hospital,Shanghai 200080Institute of Neurology,Huashan Hospital,Shanghai 200040Analytic Center of Instrument,College of Pharmacy,Shanghai Medical University 200032 |
| Abstract: | Using chronic renovascular hypertension model of Sprague-Dewley Rats, we determined that content of brain membrane free fatty acids (FFAs) in normotensive (n = 9) and hypertensive (n = 8) rats with GLC technique. The data showed that C20:4,C22 : 6 levels increased significantly (P<0. 01 ,P<0. 05) ,O18 < 0 decreased obviously (P<0. 05), and C16 :0.018 :1 increased slightly from hypertensive group (,PX). 05) as compared with normotensive group. The findings seem to reflect an abnormal metabolism of brain membrane FFAs in experimental hypertensive rats. |
| Keywords: | Rals Hypertension FFAs |
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