实行食盐碘化后对甲状腺功能亢进症发病情况的影响

目的：了解当前永川和涪陵地区甲状腺功能亢进症（甲亢）病人增多与普及全民食盐加碘的关系。方法：选择居民食用碘盐率一直较高的永川地区和居民食用碘盐率较低的涪陵地区,对1997～2008年期间发生的甲状腺功能亢进症发病率进行调查。结果：永川地区尿碘中位数271.43μg/L,涪陵地区尿碘中位数为130.68μg/L;两地发病年龄主要集中在40岁组,女性显著多于男性,约为2：1;普及碘盐后,永川地区平均甲状腺功能亢进症发病率为40.51/10万,涪陵地区为12.19/10万,两组间甲状腺功能亢进症发病率比较差异有显著性（P〈0.05）。结论：碘化食盐摄入量增多,有可能会增加甲状腺功能亢进症的发病率。

Influence of implementation of salt iodization on incidence of hyperthyroidism in Yongchuan and Fuling districts

Objective：To study the relationship between increasing hyperthyroidism and universal salt iodization in Yongchuan and Fuling districts.Methods：Yongchuan district with higher rate of consumption of iodized salt and Fuling district with lower rate of consumption of iodized salt were selected.To conduct the survey for screening hyperthyroidism patients occurred during period 1997~2008.Results：The median urinary iodine of Yongchuan and Fuling residents were 271.43 μg/L and 130.68 μg/L,respectively.The age of hyperthyroidism onset mainly located in the 40 years.The ratio was nearly 2：1 between female and male.After the universal salt iodization ,the incidence of hyperthyroidism in Yongchuan was 40.51/100000 and 12.19/100000 in Fuling,respectively.There was statistical significance between them（P0.05）.Conclusion：Excessive intake of iodized salt may increase the incidence of hyperthyroidism.