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| 高频刺激和河豚毒素对豚鼠心室肌动作电位除极启动阻滞的影响 | |
| 引用本文： | 徐心怡,沈为群,于志铭. 高频刺激和河豚毒素对豚鼠心室肌动作电位除极启动阻滞的影响[J]. 苏州大学学报(自然科学版), 1990, 0(1) |
| 作者姓名： | 徐心怡 沈为群 于志铭 |
| 作者单位： | 苏州医学院生理学教研室(徐心怡，沈为群)，苏州医学院生理学教研室(于志铭) |
| 摘 要： | 本实验应用电子计算机实时测定豚鼠心室肌动作电位,观察和分析高频刺激与河豚毒素对启动阻滞的影响。与1Hz 相比,5Hz 刺激可使启动阶段的心肌动作电位幅度、超射和最大除极速率抑制加强,心肌动作电位的频率依赖性阻滞值明显增加,反映最大除极速率动态变化的幂函数曲线弧度加大。河豚毒素可加强高频刺激时最大除极速率的启动阻滞。 |
| 关 键 词： | 动作电位 河豚毒素 心室肌 微电极 |
The Effect of High Frequency Stimulation and Tetrodotoxin on Onset Block of Depolarization of Action Potential In Guinea Pig Ventricular Muscles |
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| Xu Xinyi et al. The Effect of High Frequency Stimulation and Tetrodotoxin on Onset Block of Depolarization of Action Potential In Guinea Pig Ventricular Muscles[J]. Suzhou University Journal of Medical Science, 1990, 0(1) | |
| Authors: | Xu Xinyi et al |
| Affiliation: | Xu Xinyi et al |
| Abstract: | The effects of high frequency stimulation and TTX on onset block were analyzedby computer in guinea pig ventricular muscles.We observed that the depression ofaction potential amplitude,overshoot and V_(max) were more significant at 5Hz thanthose at 1Hz.Rate-dependent block of action potential and the radian of power fun-ction curve of the dynamic change of V(max) were increased greatly at 5 Hz.TTX en-hanced the onset block of V(max). |
| Keywords: | action potential frequency-dependent block tetrodotoxin papillary muscles microelectrode |
| 本文献已被 CNKI 等数据库收录！ | |