| 烧伤脓毒症患者血清Wnt5a水平变化及其临床意义 |
| |
| 引用本文： | 尹朝奇,贺全勇,罗成群,周建大,朱颉,李萍,陈铁夫,彭浩,徐阳成,陈佳. 烧伤脓毒症患者血清Wnt5a水平变化及其临床意义[J]. 中国全科医学, 2010, 13(11): 1165-1167 |
| |
| 作者姓名： | 尹朝奇 贺全勇 罗成群 周建大 朱颉 李萍 陈铁夫 彭浩 徐阳成 陈佳 |
| |
| 作者单位： | 长沙市,中南大学湘雅三医院烧伤整形科,湖南省,410013 |
| |
| 摘 要： | 目的 观察烧伤脓毒症患者血清Wnt5a水平变化.方法 采集烧伤脓毒症患者的血清标本,采用Western blotting法检测Wnt5a水平,并比较轻、中、重度脓毒症患者血清Wnt5a水平.同期选取轻度烧伤的非脓毒症患者8例作对照.结果 烧伤脓毒症患者血清Wnt5a水平高于对照者.动态观察发现,脓毒症痊愈后患者血清Wnt5a水平降低,而随着脓毒症病情恶化血清Wnt5a水平持续升高.结论 Wnt5a参与了烧伤患者炎症的发病过程,且检测Wnt5a水平可作为炎症严重程度的诊断指标.
|
| 关 键 词： | 烧伤 脓毒症 炎症因子 |
Study on Changes of Wnt5a Levels in Burn Patients with Sepsis |
| |
| YIN+Chao-qi,HE+Quan-yong,LUO+Cheng-qun,et+al. Study on Changes of Wnt5a Levels in Burn Patients with Sepsis[J]. Chinese General Practice, 2010, 13(11): 1165-1167 |
| |
| Authors: | YIN+Chao-qi HE+Quan-yong LUO+Cheng-qun et+al |
| |
| Affiliation: | YIN+Chao-qi,HE+Quan-yong,LUO+Cheng-qun,et+al.Department+of+Burns,Third+Xiangya+Hospital+of+Central+South+University,Changsha+410013,China |
| |
| Abstract: | Objective To investigation the changes of Wnt5a levels in burn patients with sepsis.Methods Serum samples were collected from patients with burn sepsis,and serum Wnt5a levels were compared by Western blotting assay between patients with mild,moderate or severe sepsis.Eight burn patients without sepsis enrolled as control.Results Wnt5a levels were higher in burn sepsis patients than in control.Serum Wnt5a levels reduced after sepsis was cured,but continuously elevated with the exacerbation of sepsis.Conclusi... |
| |
| Keywords: | Wnt5a Wnt5a Burns Sepsis Inflammatory cytokines |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
