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增大型甲亢^131I治疗给药系数与疗效分析
引用本文:陈会欣,宋晓范,王珉,赵景深,李紫璇,王洁.增大型甲亢^131I治疗给药系数与疗效分析[J].中国地方病防治杂志,2005,20(6):327-328.
作者姓名:陈会欣  宋晓范  王珉  赵景深  李紫璇  王洁
作者单位:吉林省地方病第二防治研究所,吉林132001
摘    要:目的 对^131I治疗甲亢常规公式增设给药系数,以提高增大型甲亢的一次治愈率,降低甲低率。方法 对比分析增加系数组116例和常规对照组143例的治愈率、甲低率、好转率、二次服药率。结果 增加系数组较对照组一次治愈率明显提高,由75.68%提高到83.62%(P〈0.01)。增加系数后痊愈率由58.04%提高到80.17%(P〈0.01);二次服药率由14.69%降到6.03%(P〈0.01);一过性甲低率和甲低率未见显著性差异。结论 增加系数后提高了增大型甲亢的一次治愈率,而甲低率未见明显增高。

关 键 词:甲状腺机能亢进症  ^131I治疗  甲状腺体积  给药系数
文章编号:1000-1889(2005)06-0327-02
收稿时间:2005-08-30
修稿时间:2005年8月30日

Clinical evaluation of ^131I dose in the treatment of Hyperthyroidism with great thyroid
CHEN Hui - xin, SONG Xiao - fan, WANG Min, et al.Clinical evaluation of ^131I dose in the treatment of Hyperthyroidism with great thyroid[J].Chinese Journal of Control of Endemic Disenaces,2005,20(6):327-328.
Authors:CHEN Hui - xin  SONG Xiao - fan  WANG Min  
Institution:The Second Institute of Prevention and Treatment for Endemic Diseases in Jilin Province, Jilin 132001 ,China
Abstract:Objective To study thyrapeutic efficacy of ~(131)I dose in treating hyperthyroidism with great thyroid.Methods Compare the fundamental healing rate and the rate of hypothyroidism on 116 cases treated by new ~(131)I calculating dose(Group 1) with 143 cases treated by originally ~(131)I calculating dose(Group 2).Results There was significant increase in cure rate,increased from(75.68%) to 83.62% in Group 1(P<0.01),and the fully recovering rate increased from 58.04% to 80.17% in Group 2(P<(0.01));There is no significant difference in hypothyroidism rate in the two groups.Conclusions We can get high cure rate by adopting new ~(131)I calculating dose with low hypothyroidism rate.
Keywords:Hyperthyrolthsm  ^131I dose  Thyroid vohmle  Calculating dose
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