住院2型糖尿病患者睡眠质量与血糖及并发症的关系

目的: 观察及评价住院的2型糖尿病（T2DM）患者睡眠质量与血糖及并发症的关系。方法:随机纳入187例住院的2型糖尿病患者，检测静脉血浆空腹血糖、餐后血糖及糖化血红蛋白，采用匹兹堡睡眠质量指数（PSQI）调查问卷评估受试者主观睡眠特征，以PSQI总分>5为睡眠质量问题组，通过Logistic回归性分析睡眠质量与血糖及并发症的关系。结果:睡眠问题组(PSQI＞5)与睡眠质量良好组（PSQI≤5）的比较，糖尿病病程、空腹血糖、糖化血红蛋白、超敏C反应蛋白（h s-CRP）及糖尿病并发症发生率在两组间有差异，且差异均有统计学意义（p均<0.05）。二元Logistic回归结果显示，睡眠质量对糖尿病患者血糖控制及其并发症发生、发展存在关联(p值均<0.05)。结论:住院的2型糖尿病患者睡眠质量与其血糖控制及其并发症的发生有密切的关系。

Relationship between sleep quality and glucose level as well as diabetic complications in hospital patients with type 2 diabetes mellitus

Objective： To observe and evaluate the relationship between sleep quality and glucose level as well as diabetic complications in patients with type 2 diabetes mellitus. Methods ：A total of 187 hospitalized type 2 diabetes were enrolled in the study. Logistic regression was performed to analyze the correction between Pittsburgh Sleep Quality Index （PSQI） score and glycemia control. The quality of sleep was assessed with PSQI. PSQI global score above 5 was defined as poor quality. Results： The following parameters differed between the two groups： the duration of diabetes, fasting plasma glucose （FPG）, hemoglobinAlc （HbAlc）, high-sensitive C-reactive protein （hs-CRP） and ratio of diabetic complications. All the above differences in parameters were statistically significant （all P〈0.05）. Binary Logistic regression analysis showed that sleep quality was correlated with glycemic control and occurrence of diabetic complications （all P〈O.05）. Conclusion： Sleep quality probably affects blood glucose regulation, and is closely correlated with the occurrence of complications in hospital patients with type 2 diabetes.