妊娠期代谢综合征诊断标准的评价及危险因素分析

目的 探讨妊娠期代谢综合征（GMS ）的诊断标准，并分析引起GM S的危险因素。方法 选取该院定期进行产科检查并住院分娩的154例单胎妊娠且子痫前期者为子痫前期组，310例妊娠期糖尿病孕妇为妊娠期糖尿病组，同时选取500例健康孕妇作为健康对照组。记录各组孕妇年龄、怀孕周数、血压、孕前体质量、孕前体质量指数，检测各组孕妇空腹血糖、胰岛素以及总胆固醇、三酰甘油、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇和游离脂肪酸的含量，并对检测结果 进行比较分析。结果 （1）子痫前期组及妊娠糖尿病组孕妇的年龄、怀孕周数、血压、孕前体质量指数分别与健康对照组比较，差异均有统计学意义（P＜0．05）。（2）子痫前期组和妊娠期糖尿病组孕妇各项检测指标分别与健康对照组比较，差异均有统计学意义（P＜0．05）。（3）子痫前期组和妊娠期糖尿病组孕妇发生GMS的风险显著升高（P＜0．05）。结论 孕前体质量指数和总胆固醇是子痫前期和妊1娠期糖尿病发生的危险因素，而两组均显示高密度脂蛋与代谢综合征的发生无显著相关。

Diagnostic criteria for metabolic syndrome during pregnancy and risk factors of evaluation

Objective To study the pregnancy was discussed in the diagnostic criteria for to study the diagnostic standard of metabolic syndrome and to analyze the risk factors caused by GMS .Methods In the city′s major obstetric gynecological hospital regularly checked and selected hospital delivery 154 cases of singleton pregnancies ,preeclampsia as preeclampsia ,gestational diabetes ,310 cases of pregnant women ,as gestational diabetes group ,while selecting 500 healthy pregnant women as a control group .Record each group maternal age ,gestational age ,blood pressure ,body weight before pregnancy ,pre-pregnancy body mass index ,to detect the group of pregnant women fasting glucose ,insulin ,and total cholesterol ,triglycerides ,HDL ,LDL and free fatty acids the content analysis of the test results .Results （1） pre-eclipse and gestational diabetes group maternal age ,gestational age ,blood pressure ,body mass index before pregnancy were compared with the control group ,the difference was statistically significant （P〈0 .05） , （2） pre-eclipse group and a group of pregnant women with gestational diabetes indicators were above the control group ,the difference was statistically significant （P〈 0 .05） ,（3） preeclampsia and gestational diabetes mellitus in pregnant women significantly increased the risk of GMS （P〈0 .05） .Conclusion Preeclampsia and gestational diabetes mellitus risk factors are pre-pregnancy body mass index and total cholesterol ,while both groups showed high density lipoprotein and incidence of metabolic syndrome was not significantly associated .