肝源性糖尿病93例临床分析

目的探讨肝源性糖尿病与慢性肝病临床类型的关系。方法对肝源性糖尿病93例临床资料进行回顾性分析。结果肝源性糖尿病的发生率在乙型肝炎患者为12.9%(93/721),其中慢性肝炎患者为33.4%(31/93),慢性重型肝炎为16.1%(15/93),肝硬化为50.5%(47/93),与慢性肝炎、慢性重型肝炎相比,差异显著(p<0.01)。肝源性糖尿病患者中血糖重度升高的比率,肝硬化与慢性肝炎、慢性重型肝炎相比,差异显著(p<0.01)。通过控制饮食、保肝、抗病毒和(或)胰岛素治疗,除2例死亡外,其他患者血糖水平均得到有效控制。结论糖尿病是慢性肝病的常见并发症,多发生于肝硬化患者,糖尿病轻重与肝损害程度成正比。在控制饮食、保肝、抗病毒和(或)胰岛素治疗后,效果较好。

THE CLINICAL RESEARCH ON 93 HEPATOGENIC DIABETES CASE

Objective To investigate the relationship between hepatogenic diabetes and chronic liver disease.Methods To retrospectively analyze clinical data of 93 hepatogenic diabetes cases.Results The incidence of hepatogenic diabetes is 12.9%(93/721)in B hepatitis,33.4%(31/93)in chronic hepatitis,16.1%(12/93)in chronic hepatic failure,50.5%(47/93)in hepatic cirrhosis patient.There is significant difference in comparing hepatic cirrhosis with chronic hepatitis and chronic hepatic failure in the incidence of hepatogenic diabetes and percentage of prominently elevated blood sugar(p<0.01).Except two dead,every patient's blood sugar is controlled effectively by diet control,liver-protecting,antivirus and /or insulin therapy.Conclusion Diabetes is familiar in chronic liver disease patients,more in hepatic cirrhosis.It is positive relation between diabetes and liver pathological changes in severity degree.Diabetes is treated effectively by diet control,liver-protecting,antivirus and /or insulin therapy.