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Letter to the Editor: Drift in the Nucleoprotein Gene of Swine Influenza Virus (H1N1) Causing Respiratory Disease in Pigs
Authors:Arora  Dharam Jit S.
Affiliation:(1) INRS-Institut Armand Frappier, University of Québec, 531 Boulevard des Prairies, Laval, H7V 1B7, Quebec, Canada
Abstract:
The nucleoprotein (NP) gene of swine influenza H1N1 variant, A/Sw/Quebec/5393/91 (SwQc91) was sequenced. When compared with other H1N1 strains, 12 amino acid (aa) replacements were observed in the 101–484 aa region of the NP protein including two aas, 345 and 430, representing the unique lineage of swine viruses. Phylogenetic analysis showed a drift in the NP gene.
Keywords:genomic drift  influenza A  nucleoprotein  swine
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