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Prevalence and correlates of epileptic seizure in substance-abusing subjects
Authors:Surendra K. Mattoo   md     Shubh M. Singh   md     Rahul Bhardwaj   md     Suresh Kumar   md  dnb   Debasish Basu   md  dnb   Parmanand Kulhara   md  frcpsych
Affiliation:Drug De-addiction and Treatment Center, Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh,;Department of Psychiatry, Gian Sagar Medical College, Banur, Punjab, India and;Campbelltown Hospital, Campbelltown, New South Wales, Australia
Abstract:Life-time prevalence of epileptic seizures was assessed in 626 consecutive patients treated for substance abuse. Seizures were reported in 8.63% (9.2% in alcohol abusers, 12.5% in opioid abusers). A total of 64.8% of the seizures were associated with substance use. These occurred during withdrawal in the alcohol cohort and during intoxication with dextropropoxyphene and withdrawal from heroin or poppy husk in the opioid cohort. Results indicate that seizures may be more common in older patients with longer duration of dependence among those abusing alcohol.
Keywords:alcohol    opioids    prevalence    seizures    substance abuse
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