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A simple in vitro technique to measure the release of endogenous dopamine and dihydroxyphenylacetic acid from striatal tissue using high performance liquid chromatography with electrochemical detection |
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| Authors: | Jill B. Becker Edward Castañeda Terry E. Robinson Mary E. Beer |
| Affiliation: | Department of Psychology and Neuroscience Laboratory Building, The University of Michigan, Ann Arbor, MI 48109 U.S.A. |
| Abstract: | An easily constructed, inexpensive and simple system is described for the superfusion of neural tissue. To characterize the system, the dynamics of endogenous dopamine and dihydroxyphenylacetic acid release from striatal tissue were studied before and after exposure to potassium, amphetamine or cocaine. |
| Keywords: | dopamine release striatum amphetamine DOPAC superfusion system endogenous neurotransmitter release dopamine |
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