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| 高效液相色谱法测定胃炎康胶囊中盐酸小檗碱的含量 | |
| 引用本文： | 李启红,于绍华,李强. 高效液相色谱法测定胃炎康胶囊中盐酸小檗碱的含量[J]. 中国民族民间医药杂志, 2010, 19(17): 18-18,20 |
| 作者姓名： | 李启红 于绍华 李强 |
| 作者单位： | 山东省东营市药品检验所,山东东营257091 |
| 摘 要： | 目的：建立高效液相色谱法测定胃炎康胶囊中盐酸小檗碱的方法。方法：采用高效液相色谱-二极管阵列检测器法，使用XDB—C18柱，流动相为乙腈-0．033mol／L磷酸二氢钾（30：70），流速1．0ml·min^-1，检测波长345nm。结果：盐酸小檗碱在4．88～48．8mg／L内咎性良好，平均回收率100．09％（t=0．9978）。结论：本方法操作简便、灵敏、准确，可用于该制剂的质量控制。 |
| 关 键 词： | 胃炎康胶囊 盐酸小檗碱 高效液相色谱法 |
Determining the Content of Berberine Hydrochloride in Weiyan kang Capsule by High Pressure Liquid Chromatography(HPLC) |
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| LI Qi - hong,YU Shao - hua,LI Qiang. Determining the Content of Berberine Hydrochloride in Weiyan kang Capsule by High Pressure Liquid Chromatography(HPLC)[J]. Chinese Journal of Ethnomedicine and Ethnopharmacy, 2010, 19(17): 18-18,20 | |
| Authors: | LI Qi - hong YU Shao - hua LI Qiang |
| Affiliation: | (Dongying Institute for Drug Control, Dongying 257091 ) |
| Abstract: | Objective： To establish a HPLC method for the determination of Berberine Hydrochloride in weiyan kang. Methods： HPLC - DAD analysis was carried out on XDB - C18 column With acetonitrile -0. 033mol/LPotassium dihydrogen phosphate solution （30： 70） as the mobile phase. The detection wavelength was 345nm and the flow rate was 1.0ml · min^-1. Results： the linear range of Berberine Hydrochloride was 4. 88-48. 8mg/L with average rate of recovery 100. 09% （r =0. 9998）. Conclusion： The method is simple accurate and reliable, it an be a quality control standard of weiyan kang. |
| Keywords: | weiyan kang Capsule Berberine Hydrochloride HPLC |
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